SAB4501063

Anti-GABBR1 antibody produced in rabbit

affinity isolated antibody

• Synonym(e): γ-aminobutyric acid type B receptor subunit 1, GABA-B receptor 1, GABA-B-R1, GABBR1, Gb1
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 108 kDa
• Speziesreaktivität: mouse, human, rat
• Konzentration: ~1 mg/mL
• Methode(n): ELISA: 1:1000; immunofluorescence: 1:100-1:500; western blot: 1:500-1:1000
• NCBI-Hinterlegungsnummer: Q9UBS5
• UniProt-Hinterlegungsnummer: Q9UBS5
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... GABBR1(2550)

Beschreibung

Allgemeine Beschreibung

Anti-GABBR1 Antibody detects endogenous levels of total GABBR1 protein.

The γ-aminobutyric acid type B (GABAB) receptor is coded by the GABBR1 gene. It has 22 exons and spans at least 18 kb. GABAB geneis present between an olfactory receptor gene cluster downstream and the HLA (human leukocyte antigen) class I region upstream. It is mapped to human chromosome 6p22.

Immunogen

The antiserum was produced against synthesized peptide derived from human GABBR1.

Immunogen Range: 891-940

Biochem./physiol. Wirkung

The γ-aminobutyric acid type B (GABAB) is essential for the initiation by agonists like GABA (gamma-aminobutyric acid ). GABAB receptors participates in response habituation. In the visual cortex, GABAB is also involved in the initiation of orientation tuning in conjunction with GABAA receptors.

Leistungsmerkmale und Vorteile

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Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable