SAB4300529

Anti-α-Synuclein (SNCA) Antibody

rabbit polyclonal

• Synonym(e): Anti-NACP antibody produced in rabbit, Anti-alphaSYN antibody produced in rabbit, Anti-synuclein, alpha antibody produced in rabbit
• UNSPSC Code: 12352203
• NACRES: NA.41
• MDL number: MFCD02095740
• Conjugate: unconjugated
• Clone: polyclonal
• Application: IF, WB
• Citations: -

Eigenschaften

• Produktname: Anti-Snca (Ab-136) antibody produced in rabbit, affinity isolated antibody
• biological source: rabbit
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: ~18 kDa
• species reactivity: mouse, human, rat
• concentration: 1 mg/mL
• technique(s): indirect immunofluorescence: 1:100-1:200, western blot: 1:500-1:1000
• isotype: IgG
• immunogen sequence: (Q-D-Y-E-P)
• NCBI accession no.: NP_001035916.1
• UniProt accession no.: P37840
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: mouse ... Snca(20617)

Beschreibung

General description

May be involved in the regulation of dopamine release and transport. Soluble protein, normally localized primarily at the presynaptic region of axons, which can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies). Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.

Immunogen

Peptide sequence around aa. 134-138 (Q-D-Y-E-P), according to the protein Snca.

Features and Benefits

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Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklasse: 10 - Combustible liquids
• Was ist los?: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable