SAB3500711

Anti-TET2 antibody produced in rabbit

affinity isolated antibody

• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Mol-Gew.: 220 kDa
• Speziesreaktivität: human
• Konzentration: 1 mg/mL
• Methode(n): ELISA: suitable; western blot: suitable
• NCBI-Hinterlegungsnummer: NP_001120680
• UniProt-Hinterlegungsnummer: Q6N021
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... TET2(54790)

Beschreibung

Allgemeine Beschreibung

Tet methylcytosine dioxygenase 2 (TET2) is part of the Fe(II)/α-ketoglutarate-dependent dioxygenase family of enzymes. It is expressed in the brain. The gene encoding TET2 is localized on human chromosome 4q24.

Immunogen

Antibody was raised against an 18 amino acid peptide near the amino terminus of human TET2.

Anwendung

Anti-TET2 antibody produced in rabbit has been used in Western blotting.

Biochem./physiol. Wirkung

Tet methylcytosine dioxygenase 2 (TET2) is involved in the conversion of 5-methylcytosine to 5-hydroxymethyl-cytosine (5hmC). It also has a role in stimulating DNA demethylation and lymphomagenesis. Mutations in the gene encoding TET2 have been linked to myelodysplastic syndromes.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Verlinkung

The action of this antibody can be blocked using blocking peptide SBP3500711.

Physikalische Form

Supplied at 1 mg/mL in PBS with 0.02% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable