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SAB2701800

Sigma-Aldrich

Anti-sox2 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(e):

cb236, sox2, wu:fb83g04, wu:fc14d07

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Speziesreaktivität

zebrafish, (Japanese Medaka)

Methode(n)

immunohistochemistry: suitable
western blot: suitable

NCBI-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

−20°C

Angaben zum Gen

human ... sox2(378723)

Immunogen

Recombinant protein containing a sequence corresponding to a region within amino acids 42 and 238 of sox2 according to NP_998283

Anwendung

Suggested starting dilutions are as follows: IHC-Fr: 1:100-1:1000, IHC-P: Assay-dependent dilution, WB: Assay-dependent dilution, IHC-Wm: 1:50-1:500. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

Biochem./physiol. Wirkung

Transcriptional activator. May function as a switch in neuronal development.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Piktogramme

Exclamation markEnvironment

Signalwort

Warning

Gefahreneinstufungen

Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Jolien Van Houcke et al.
NPJ Regenerative medicine, 8(1), 31-31 (2023-06-17)
The young African turquoise killifish has a high regenerative capacity, but loses it with advancing age, adopting several aspects of the limited form of mammalian regeneration. We deployed a proteomic strategy to identify pathways that underpin the loss of regenerative
Jolien Van Houcke et al.
Aging cell, 20(9), e13464-e13464 (2021-08-25)
The aging central nervous system (CNS) of mammals displays progressive limited regenerative abilities. Recovery after loss of neurons is extremely restricted in the aged brain. Many research models fall short in recapitulating mammalian aging hallmarks or have an impractically long
Kyeong-Hye Moon et al.
eLife, 9 (2021-01-01)
Defective primary cilia cause a range of diseases known as ciliopathies, including hearing loss. The etiology of hearing loss in ciliopathies, however, remains unclear. We analyzed cochleae from three ciliopathy mouse models exhibiting different ciliogenesis defects: Intraflagellar transport 88 (Ift88)
Sophie Vanhunsel et al.
NPJ aging and mechanisms of disease, 7(1), 22-22 (2021-08-19)
Worldwide, people are getting older, and this prolonged lifespan unfortunately also results in an increased prevalence of age-related neurodegenerative diseases, contributing to a diminished life quality of elderly. Age-associated neuropathies typically include diseases leading to dementia (Alzheimer's and Parkinson's disease)
Fei Yan et al.
Frontiers in cell and developmental biology, 8, 585251-585251 (2021-01-12)
Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death. This study aimed to examine the roles of DHRS4-AS1/miR-224-3p signaling in the cancer cell stemness of NSCLC. Real-time PCR showed that DHRS4-AS1 was downregulated in cancerous tissues, and

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