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S8192

Sigma-Aldrich

Anti-phospho-Synapsin I (pSer603) antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

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About This Item

MDL-Nummer:
MFCD03792019
UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

200

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Speziesreaktivität

mouse, Xenopus, bovine, human, zebrafish, rat

Konzentration

~1 mg/mL

Methode(n)

western blot: 1:1,000 using rat brain hipoccampal tissue homogenate

UniProt-Hinterlegungsnummer

P17600

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

phosphorylation (pSer603)

Angaben zum Gen

human ... SYN1(6853)
mouse ... Syn1(20964)
rat ... Syn1(24949)

Immunogen

synthetic phosphorylated peptide derived from the region of rat synapsin I that is phosphorylated on serine 603.

Anwendung

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Physikalische Form

Solution in 10 mM HEPES buffer, pH 7.5, and 150 mM NaCl containing 100 μg/ml bovine serum albumin and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Heather D VanGuilder et al.
The European journal of neuroscience, 28(1), 1-11 (2008-07-30)
Diabetic retinopathy can result in vision loss and involves progressive neurovascular degeneration of the retina. This study tested the hypothesis that diabetes decreases the retinal expression of presynaptic proteins involved in synaptic function. The protein and mRNA contents for synapsin
Jing Zhang et al.
Journal of neuroendocrinology, 25(8), 753-761 (2013-05-18)
Hypothalamic glutamate (Glu) and γ-GABA neurotransmission are involved in the ovarian hormone-induced gonadotrophin-releasing hormone (GnRH)/luteinising hormone (LH) surge in rodents. Studies have shown that reduced Glu and increased γ-GABA in the rostral preoptic area (rPOA) of the hypothalamus, where most
Zhenxia Qin et al.
PloS one, 8(11), e80758-e80758 (2013-11-14)
Isoaspartate (isoAsp) formation is a major source of protein damage that is kept in check by the repair function of protein L-isoaspartyl methyltransferase (PIMT). Mice deficient in PIMT accumulate isoAsp-containing proteins, resulting in cognitive deficits, abnormal neuronal physiology and cytoarchitecture
Dillon Y Chen et al.
Nature neuroscience, 15(12), 1707-1714 (2012-11-20)
Emotionally important events are well remembered. Although memories of emotional experiences are known to be mediated and modulated by stress hormones such as glucocorticoids, little is known about the underlying molecular mechanisms. We found that the hippocampal glucocorticoid receptors that

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