S8065

Amyloid Precursor Protein α (304-612), Secreted human

>90% (SDS-PAGE), recombinant, expressed in E. coli (N-terminal histidine tagged), buffered aqueous solution

• Synonym(e): sAPPα (304-612)
• UNSPSC Code: 12352200
• NACRES: NA.32
• MDL number: MFCD03791389

Eigenschaften

• recombinant: expressed in E. coli (N-terminal histidine tagged)
• assay: >90% (SDS-PAGE)
• form: buffered aqueous solution
• mol wt: apparent mol wt ~45 kDa by SDS-PAGE
• UniProt accession no.: P05067
• shipped in: dry ice
• storage temp.: −70°C
• Gene Information: human ... APP(351)

Beschreibung

Biochem/physiol Actions

Fragment of sAPPα designed to lack the N-terminal domain of the full length protein.

Secreted Amyloid Precursor Protein α (sAPPα) is a 612 amino acid protein produced from the ubiquitously expressed β-Amyloid precursor protein (βAPP), 695 isoform, by α-secretase cleavage. sAPPα (304-612) is a fragment of sAPPα designed to lack the N-terminal domain of the full length protein.

Physical form

0.2 μm filtered solution in phosphate buffered saline, pH 7.4.

Preparation Note

Expressed as a soluble protein and purified under non-denaturing conditions.