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Merck

S2442

Sigma-Aldrich

S9 from Liver, Pooled

from human

Synonym(e):

Liver S9 Fraction, S9 Liver Extract

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About This Item

UNSPSC-Code:
12161501
NACRES:
NA.47

Biologische Quelle

human

Qualitätsniveau

Verpackung

vial of ~20 mg

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Lagertemp.

−70°C

Angaben zum Gen

human ... RPS9(6203)

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Anwendung

Pooled S9 fractions from liver have been used for genotoxicity experiments.

Biochem./physiol. Wirkung

The hepatic S9 pools from a variety of biological sources represent the post-mitochondrial supernatant fraction from homogenized liver. Known to be a rich source of drug metabolizing enzymes including P-450, these pools are useful in the study of xenobiotic metabolism and drug interactions.
The hepatic S9 pools from a variety of biological sources represent the post-mitochondrial supernatant fraction from homogenized liver. They are known to be a rich source of drug metabolizing enzymes including P-450. S9 pools are useful in the study of xenobiotic metabolism and drug interactions. They are used in the Ames test, which is a method that uses bacteria to test if a given chemical causes mutations in the genetic material of a given test organism.

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

A conjugate of pyridine-4-aldoxime and atropine as a potential
antidote against organophosphorus compounds poisoning
Jasna Lovric
Acta Biochimica Polonica, 58(2) (2011)
The Ames Salmonella/microsome mutagenicity assay.
Mortelmans K and Zeiger E
Mutation Research (2000)
Marina Paul et al.
Reproductive sciences (Thousand Oaks, Calif.) (2023-02-11)
The mechanism by which human labor is initiated in the presence of elevated circulating progesterone levels remains unknown. Recent evidence indicates that the progesterone-metabolizing enzyme, 20α-hydroxysteroid dehydrogenase (20α-HSD), encoded by the gene AKR1C1, may contribute to functional progesterone withdrawal. We
Implementation of the Three Rs in the Human Hazard
Assessment of Brazilian Medicinal Plants: An Evaluation
of the Cytotoxic and Genotoxic Potentials of Dipteryx
alata Vogel
Natalia M. Esteves-Pedro
Alberta RN / Alberta Association of Registered Nurses (2011)
An improvement of the Ames test using a modified human liver S9 preparation.
Hakura A
Journal of Pharmacological and Toxicological Methods, 169-172 (2001)

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