S1450

Anti-Superoxide Dismutase (MnSOD) (DD-17)−Cy3 antibody produced in rabbit

1-2 mg/mL, affinity isolated antibody, buffered aqueous solution

• Synonym(e): Anti-IPO-B, Anti-Indophenoloxidase B, Anti-MNSOD, Anti-Manganese Superoxide Dismutase 2, Anti-Manganese dependent SOD, Anti-Mitochondrial SOD, Anti-SOD2, Anti-Superoxide dismutase 2
• UNSPSC-Code: 12352203
• NACRES: NA.43

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: CY3 conjugate
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Speziesreaktivität: human, rat, mouse
• Verpackung: antibody small pack of 25 μL
• Konzentration: 1-2 mg/mL
• Methode(n): direct immunofluorescence: 2-5 μg/mL using human HeLa, rat NRK and mouse 3T3 cells.
• UniProt-Hinterlegungsnummer: P04179
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... SOD2(6648)

Beschreibung

Allgemeine Beschreibung

The SOD2 (superoxide dismutase 2) gene is mapped to human chromosome 6q25.3. The encoded protein functions as a tetramer and is localized to mitochondria.

Immunogen

synthetic peptide corresponding to amino acid residues 183-199 of human superoxide dismutase (MnSOD), conjugated to KLH. The corresponding sequence is conserved in many eukaryotes.

Anwendung

Anti-Superoxide Dismutase (MnSOD) (DD-17)-Cy3 antibody produced in rabbit has been used in immunohistochemistry.

Biochem./physiol. Wirkung

Superoxide dismutase 2 (SOD2) is an antioxidant enzyme and catalyzes the conversion of superoxide to hydrogen peroxide and molecular oxygen. The enzyme offers protection against oxidative damage induced by reactive oxygen species and is also radioprotective. The gene is associated with the metastasis and invasion process of salivary adenoid cystic carcinoma. Manganese SOD is involved in detoxification.

Physikalische Form

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable