RAB0606

Human ANGPTL3 / Angiopoietin-related Protein 3 ELISA Kit

Name: Human ANGPTL3 / Angiopoietin-related Protein 3 ELISA Kit
Brand: SIGMA
Price: 571 EUR

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96 WELLS

€ 571,00

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Über diesen Artikel

NACRES:

NA.32

UNSPSC Code:

41116158

Gene information:

human ... ANGPTL3(27329)

Input:

sample type plasma
sample type cell culture supernatant(s)
sample type serum

Species reactivity:

human

Storage temp.:

−20°C

Shipped in:

wet ice

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Unterstützung erhalten

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type plasma
sample type cell culture supernatant(s)
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 8.2 pg/mL
standard curve range: 8.19-2000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... ANGPTL3(27329)

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Dieser Artikel	RAB0017	RAB1264	RAB0015
Sigma-Aldrich RAB0606 Human ANGPTL3 / Angiopoietin-related Protein 3 ELISA Kit	Sigma-Aldrich RAB0017 Human ANGPTL4 ELISA Kit	Sigma-Aldrich RAB1264 Human ANGPTL7 ELISA	Sigma-Aldrich RAB0015 Human Angiopoietin-1 ELISA Kit
Gene Information human ... ANGPTL3(27329)	Gene Information human ... ANGPTL4(51378)	Gene Information human ... ANGPTL7(10218)	Gene Information human ... ANGPT1(284)
species reactivity human	species reactivity human	species reactivity human	species reactivity human
assay range inter-assay cv: <12% intra-assay cv: <10% sensitivity: 8.2 pg/mL standard curve range: 8.19-2000 pg/mL	assay range inter-assay cv: <12% intra-assay cv: <10% sensitivity: 20 pg/mL standard curve range: 27.4-20000 pg/mL	assay range inter-assay cv: <12% intra-assay cv: <10% sensitivity: 0.05 ng/mL standard curve range: 0.049-12 ng/mL	assay range inter-assay cv: <12% intra-assay cv: <10% sensitivity: 30 pg/mL standard curve range: 74.07-18000 pg/mL
input sample type plasma sample type cell culture supernatant(s) sample type serum	input sample type cell culture supernatant(s) sample type serum sample type plasma	input sample type cell culture supernatant(s) sample type plasma sample type serum	input sample type urine sample type plasma sample type cell culture supernatant(s) sample type serum
technique(s) ELISA: suitable	technique(s) ELISA: suitable, capture ELISA: suitable	technique(s) ELISA: suitable	technique(s) ELISA: suitable, capture ELISA: suitable
detection method colorimetric	detection method colorimetric	detection method colorimetric	detection method colorimetric

General description

Angiopoietin-related protein 3 (ANGPTL3) is a member of the ANGPTL family and is expressed in the liver.[1] The ANGPTL3 gene is mapped on the human chromosome at 1p31.3.[2] Mutations in the ANGPTL3 gene lead to familial combined hypolipidemia, a Mendelian condition that is indicated by lower levels of triglycerides, high-density lipoprotein (HDL), and low-density lipoprotein cholesterol.[3] The ANGPTL3 enzyme-linked immunosorbent assay (ELISA) kit provides for the quantitative measurement of angiopoietin-related protein 3 in cell culture supernatants, plasma, and serum.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Kit-Komponenten auch einzeln erhältlich

Produkt-Nr.

Beschreibung

SDB

RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDB

RABSTOP3ELISA Stop Solution (Item I)SDB

RABWASH420X Wash Buffer (Item B)SDB

pictograms

GHS05

signalword

Warning

hcodes

H290

pcodes

P234 - P390

Hazard Classifications

Met. Corr. 1

Lagerklasse

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Serum angiopoietin-like 3 levels are elevated in obese non diabetic men but are unaffected during an oral glucose tolerance test.

Maria Fernanda Garcés et al.

Scientific reports, 10(1), 21118-21118 (2020-12-05)

This study aimed to determine ANGPTL3 serum levels in healthy young lean and obese non-diabetic men during an oral glucose tolerance test (OGTT) and correlate them with anthropometric, biochemical and hormonal parameters. A case-control study was carried out and 30

Atypical angiopoietin-like protein that regulates ANGPTL3.

Fabiana Quagliarini et al.

Proceedings of the National Academy of Sciences of the United States of America, 109(48), 19751-19756 (2012-11-15)

Angiopoietin-like proteins (ANGPTLs) play major roles in the trafficking and metabolism of lipids. Inactivation of ANGPTL3, a gene located in an intron of DOCK7, results in very low levels of LDL-cholesterol (C), HDL-C and triglyceride (TAG). We identified another ANGPTL

High Copy-Number Variation Burdens in Cranial Meningiomas From Patients With Diverse Clinical Phenotypes Characterized by Hot Genomic Structure Changes.

Junpeng Ma et al.

Frontiers in oncology, 10, 1382-1382 (2020-09-15)

Meningiomas, as the most common primary tumor of the central nervous system, are known to harbor genomic aberrations that associate with clinical phenotypes. Here we performed genome-wide genotyping for cranial meningiomas in 383 Chinese patients and identified 9,821 copy-number variations

Role of angiopoietin-like protein 3 in sugar-induced dyslipidemia in rhesus macaques: suppression by fish oil or RNAi.

Andrew A Butler et al.

Journal of lipid research, 61(3), 376-386 (2020-01-11)

Angiopoietin-like protein 3 (ANGPTL3) inhibits lipid clearance and is a promising target for managing cardiovascular disease. Here we investigated the effects of a high-sugar (high-fructose) diet on circulating ANGPTL3 concentrations in rhesus macaques. Plasma ANGPTL3 concentrations increased ∼30% to 40%

ANGPTL3 Deficiency and Protection Against Coronary Artery Disease.

Nathan O Stitziel et al.

Journal of the American College of Cardiology, 69(16), 2054-2063 (2017-04-08)

Familial combined hypolipidemia, a Mendelian condition characterized by substantial reductions in all 3 major lipid fractions, is caused by mutations that inactivate the gene angiopoietin-like 3 (ANGPTL3). Whether ANGPTL3 deficiency reduces risk of coronary artery disease (CAD) is unknown. The study

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Global Trade Item Number

SKU	GTIN
RAB0606-1KT	04061835164080

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