PZ0129

CP-380736

≥98% (HPLC)

• Synonym(e): 6,7-Bis(2-methoxyethoxy)-3,4-dihydroquinazolin-4-one, 6,7-Bis(2-methoxyethoxy)-4(3H)-quinazolinone, PF-00520893
• Empirische Formel (Hill-System): C₁₄H₁₈N₂O₅
• CAS-Nummer: 179688-29-0
• Molekulargewicht: 294.30
• NACRES: NA.77
• PubChem Substance ID: 329823716
• UNSPSC Code: 51111800
• MDL number: MFCD02678087
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: off-white to light tan
• solubility: DMSO: ≥10 mg/mL
• storage temp.: room temp
• SMILES string: COCCOc1cc2N=CNC(=O)c2cc1OCCOC
• InChI: 1S/C14H18N2O5/c1-18-3-5-20-12-7-10-11(15-9-16-14(10)17)8-13(12)21-6-4-19-2/h7-9H,3-6H2,1-2H3,(H,15,16,17)
• InChI key: PMQWTUWLIGJTQD-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

CP-380736 is an inhibitor of the epidermal growth factor receptor (EGFR). EGFR is a tyrosine kinase that activates MAPK, JNK, and Akt pathways, and is an important mediator of several types of cancer, including lung cancer and glioblastoma multiforme.

CP-380736 is selective inhibitor of epidermal growth factor receptor.

Features and Benefits

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable