P9797

Pyridostigminbromid

≥98% (HPLC), Acetylcholinesterase inhibitor, solid

• Synonym(e): 3-(Dimethylaminocarbonyloxy)-1-methylpyridiniumbromid
• Empirische Formel (Hill-System): C₉H₁₃BrN₂O₂
• CAS-Nummer: 101-26-8
• Molekulargewicht: 261.12
• NACRES: NA.77
• PubChem Substance ID: 24277865
• UNSPSC Code: 12352200
• EC Number: 202-929-9
• MDL number: MFCD00079283
• Assay: ≥98% (HPLC)
• Form: solid

Eigenschaften

• Produktname: Pyridostigminbromid,
• assay: ≥98% (HPLC)
• Quality Segment: 100
• form: solid
• solubility: water: 100 mg/mL, clear to very slightly hazy, colorless
• originator: Valeant
• SMILES string: [Br-].CN(C)C(=O)Oc1ccc[n+](C)c1
• InChI: 1S/C9H13N2O2.BrH/c1-10(2)9(12)13-8-5-4-6-11(3)7-8;/h4-7H,1-3H3;1H/q+1;/p-1
• InChI key: VNYBTNPBYXSMOO-UHFFFAOYSA-M
• Gene Information: human ... ACHE(43)

Beschreibung

Application

Pyridostigmine bromide has been used as a cholinesterase inhibitor in mice, in florimetric assay for acetylcholine secretion and for measuring acetylcholine release from mice atrial tissue.

Biochem/physiol Actions

Pyridostigmine bromide inhibits acetylcholine esterase and is membrane impermeable. It is used as a preventive medicine in chemical warfare. Pyridostigmine bromide is a carbamate compound comprising quaternary amine structure. It displays low absorption at the gastrointestinal tract. Sustained release of pyridostigmine is recommended for improving its bioavailability in treating myasthenia gravis.

Acetylcholinesterase Inhibitor.

Features and Benefits

This compound was developed by Valeant. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• pictograms: GHS06
• signalword: Danger
• hcodes: H300 + H310 + H330,H317
• Hazard Classifications: Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Skin Sens. 1
• Lagerklasse: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 3
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
• pcodes: P260 - P262 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• flash_point_f: No data available
• flash_point_c: No data available