The stability of this product in solution has not been investigated, but is believed to be quite stable. The Certified Reference Material, product P-078, is a 1 mg/mL solution in methanol that is assigned a shelf life of approximately 5 years when stored frozen at ?20°C. Please see the link below to review a publication that reports aqueous solutions are stable for at least 66 days at room temperature.
https://onlinelibrary.wiley.com/doi/10.1111/j.1365-2710.1986.tb00872.x
Fortfahren mit
P6126
(R)-(−)-Phenylephrin -hydrochlorid
≥99% (titration), powder, α₁-adrenoceptor agonist
Synonym(e):
(R)-(−)-1-(3-Hydroxyphenyl)-2-methylaminoethanol -hydrochlorid, (R)-(−)-3-Hydroxy-α-(methylaminomethyl)-benzylalkohol -hydrochlorid
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| Größe/SKU | Verfügbarkeit | Preis |
|---|---|---|
5 g | Warenkorb auf Verfügbarkeit prüfen | € 70,80 |
10 g | Warenkorb auf Verfügbarkeit prüfen | € 127,00 |
25 g | Warenkorb auf Verfügbarkeit prüfen | € 260,00 |
50 g | Warenkorb auf Verfügbarkeit prüfen | € 424,00 € 360,40 |
100 g | Warenkorb auf Verfügbarkeit prüfen | € 607,00 |
Über diesen Artikel
Lineare Formel:
HOC6H4CH(CH2NHCH3)OH·HCl
CAS-Nummer:
Molekulargewicht:
203.67
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
200-517-3
MDL number:
Beilstein/REAXYS Number:
4158948
Form:
powder
Technischer Dienst
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Unterstützung erhaltenProduktname
(R)-(−)-Phenylephrin -hydrochlorid, powder
form
powder
Quality Segment
mp
143-145 °C (lit.)
originator
Johnson & Johnson
SMILES string
OC1=CC([C@H](CNC)O)=CC=C1.Cl
InChI
1S/C9H13NO2.ClH/c1-10-6-9(12)7-3-2-4-8(11)5-7;/h2-5,9-12H,6H2,1H3;1H/t9-;/m0./s1
InChI key
OCYSGIYOVXAGKQ-FVGYRXGTSA-N
Gene Information
human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)
General description
(R)-(-)-Phenylephrine hydrochloride is an adrenergic agent, which functions as a β-receptor sympathomimetic drug.
Application
(R)-(-)-Phenylephrine hydrochloride has been used:
- in the preparation and culturing of cardiocytes and fibroblasts
- to stimulate myocardial strips to measure slice contraction
- in primary cardiomyocyte culture to show the effect of Kruppel-like factors (KLF) on cardiac hypertrophy in vivo
- to evaluate the pharmacological response of embryonic stem cell (ESC)-derived cardiomyocytes
- to pharmacologically rescue GATA (erythroid transcription factor) binding protein 3 (GATA3) null embryo from early embryonic lethality
Biochem/physiol Actions
α1-Adrenoceptor Agonist.
Features and Benefits
This compound is featured on the α1-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
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Dieser Artikel | |||
|---|---|---|---|
| description powder | description analytical standard | description United States Pharmacopeia (USP) Reference Standard | description British Pharmacopoeia (BP) Reference Standard |
| form powder | form powder | form - | form powder |
| Quality Level 200 | Quality Level 200 | Quality Level - | Quality Level - |
| originator Johnson & Johnson | originator - | originator - | originator - |
| mp 143-145 °C (lit.) | mp 143-145 °C (lit.) | mp 143-145 °C (lit.) | mp 143-145 °C (lit.) |
| Gene Information human ... ADRA1A(148), ADRA1B(147), ADRA1D(146) | Gene Information human ... ADRA1A(148), ADRA1B(147), ADRA1D(146) | Gene Information human ... ADRA1A(148), ADRA1B(147), ADRA1D(146) | Gene Information human ... ADRA1A(148), ADRA1B(147), ADRA1D(146) |
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Explore all of our products under (R)-(−)-Phenylephrin -hydrochlorid
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Skin Sens. 1B
Lagerklasse
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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What are the recommended storage temperature and duration for the substance in solution?
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How to dissolve the power of PE.
1 answer-
The product is tested for solubility at 50 mg/ml in water. This information can be found in the specification sheet or Certificate of Analysis accessible from the Product Detail Page.
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What is the Department of Transportation shipping information for this product?
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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Is (R)-(-)-Phenylephrine hydrochloride the same as L-Phenylephrine hydrochloride?
1 answer-
(R)-(-)-Phenylephrine hydrochloride is also named l-Phenylephrine hydrochloride (lower case el) or Levophenylephrine hydrochloride.
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