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Merck

P4429

Pancreozymin from porcine intestine

2-6 Crick units/mg solid

Synonym(e):

CCK, Cholecystokinin

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Über diesen Artikel

CAS-Nummer:
NACRES:
NA.54
UNSPSC Code:
12352204
MDL number:
Specific activity:
2-6 Crick units/mg solid

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Unterstützung erhalten

form

solid

Quality Level

specific activity

2-6 Crick units/mg solid

foreign activity

secretin 0.4 - 1.0 Crick units/mg solid

storage temp.

2-8°C

InChI

1S/C166H261N51O52S4/c1-15-84(9)130(159(261)211-116(78-220)154(256)206-110(68-125(227)228)150(252)191-97(38-27-54-182-165(176)177)139(241)205-112(70-127(231)232)152(254)215-132(88-42-44-91(45-43-88)269-273(266,267)268)161(263)197-100(48-58-270-12)135(237)185-75-124(226)190-106(64-89-72-184-94-35-21-20-33-92(89)94)146(248)195-101(49-59-271-13)141(243)204-111(69-126(229)230)151(253)198-103(133(173)235)63-87-31-18-17-19-32-87)213-143(245)98(39-28-55-183-166(178)179)192-147(249)107(65-90-73-180-80-187-90)201-153(255)115(77-219)210-157(259)119-41-30-57-217(119)163(265)113(71-128(233)234)207-145(247)105(62-82(5)6)200-149(251)109(67-122(172)224)203-140(242)99(46-47-120(170)222)193-144(246)104(61-81(3)4)199-148(250)108(66-121(171)223)202-138(240)96(36-23-25-52-168)196-158(260)129(83(7)8)212-160(262)131(85(10)16-2)214-155(257)117(79-221)208-142(244)102(50-60-272-14)194-137(239)95(37-26-53-181-164(174)175)189-123(225)74-186-136(238)114(76-218)209-156(258)118-40-29-56-216(118)162(264)86(11)188-134(236)93(169)34-22-24-51-167/h17-21,31-33,35,42-45,72-73,80-86,93,95-119,129-132,184,218-221H,15-16,22-30,34,36-41,46-71,74-79,167-169H2,1-14H3,(H2,170,222)(H2,171,223)(H2,172,224)(H2,173,235)(H,180,187)(H,185,237)(H,186,238)(H,188,236)(H,189,225)(H,190,226)(H,191,252)(H,192,249)(H,193,246)(H,194,239)(H,195,248)(H,196,260)(H,197,263)(H,198,253)(H,199,250)(H,200,251)(H,201,255)(H,202,240)(H,203,242)(H,204,243)(H,205,241)(H,206,256)(H,207,247)(H,208,244)(H,209,258)(H,210,259)(H,211,261)(H,212,262)(H,213,245)(H,214,257)(H,215,254)(H,227,228)(H,229,230)(H,231,232)(H,233,234)(H4,174,175,181)(H4,176,177,182)(H4,178,179,183)(H,266,267,268)

InChI key

QFLBZJPOIZFFJQ-UHFFFAOYSA-N

Application

Cholecystokinin (CCK) is a peptide hormone of the gastrointestinal system responsible for stimulating the digestion of fat and protein. It is used to study brain, kidney and pancreatic functioning as well as reproductive behavior and glucose tolerance[1][2].

Biochem/physiol Actions

CCK mediates digestion and satiety. It has anti-inflammatory properties. CCK stimulates insulin secretion through phospholipase activity in b-cells[2].

Lagerklasse

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Die Dokumentenbibliothek aufrufen

Alan R Mackie et al.
American journal of physiology. Gastrointestinal and liver physiology, 304(11), G1038-G1043 (2013-04-13)
The aim of this study was to determine the extent to which gastric layering and retention of a meal could be used to reduce appetite using the same caloric load. Liquid (control) and semi-solid (active) meals were produced with the
Sam A Booker et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(18), 7961-7974 (2013-05-03)
Inhibitory parvalbumin-containing interneurons (PVIs) control neuronal discharge and support the generation of theta- and gamma-frequency oscillations in cortical networks. Fast GABAergic input onto PVIs is crucial for their synchronization and oscillatory entrainment, but the role of metabotropic GABA(B) receptors (GABA(B)Rs)
Utilization of cholecystokinin cholescintigraphy in clinical practice.
Bryan K Richmond et al.
Journal of the American College of Surgeons, 217(2), 317-323 (2013-06-05)
Crick, J., et al.
The Journal of Physiology, 110, 110-110 (1950)
A neuroendocrine tumor syndrome from cholecystokinin secretion.
Jens F Rehfeld et al.
The New England journal of medicine, 368(12), 1165-1166 (2013-03-22)

Global Trade Item Number

SKUGTIN
P4429-25UN04061832758930

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