P3662

Natriumpyruvat

Hybri-Max^™, powder, suitable for hybridoma

• Synonym(e): α-Ketopropionsäure Natriumsalz, 2-Oxopropionsäure Natriumsalz, Brenztraubensäure Natriumsalz, Pyruvat Natrium
• Lineare Formel: CH₃COCOONa
• CAS-Nummer: 113-24-6
• Molekulargewicht: 110.04
• UNSPSC Code: 12352205
• NACRES: NA.75
• PubChem Substance ID: 24898440
• EC Number: 204-024-4
• Beilstein/REAXYS Number: 3568341
• MDL number: MFCD00002586

Eigenschaften

• biological source: synthetic (organic)
• Quality Segment: 200
• grade: Hybri-Max^™
• assay: ≥99%
• form: powder
• technique(s): cell culture | hybridoma: suitable
• impurities: endotoxin, tested
• mp: >300 °C (lit.)
• solubility: H₂O: 100 mg/mL
• shipped in: ambient
• storage temp.: 2-8°C
• SMILES string: [Na+].CC(=O)C([O-])=O
• InChI: 1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1
• InChI key: DAEPDZWVDSPTHF-UHFFFAOYSA-M

Beschreibung

Application

Sodium pyruvate is used by cells as an easily accessible carbohydrate source. Additionally, it is involved with amino acid metabolism and initiates the Kreb′s cycle. The 100 mM solution should be diluted 1:100 for most cell culture applications.

Sodium pyruvate has been used as a component in maturation medium for oocyte evaluation.

Biochem/physiol Actions

Sodium pyruvate is known to be an effective therapeutic target for type II citrullinaemia which is characterized by hyperammonaemia. In vivo studies proves that sodium pyruvate has protective function against hemorrhagic shock by preventing lipid peroxidation, NAD+ reduction and cleavage of poly(ADP-ribose) polymerases. Sodium pyruvate is also known to possess anti-inflammatory action and might show improvement in chronic lung disorder.

Legal Information

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H317,H319
• pcodes: P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Sens. 1B
• Lagerklasse: 13 - Non Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)