Product O9389, Oltipraz, has no Retest or Expiration Date. There are a number of products with the only date shown on the lot-specific Certificate of Analysis being the Release Date. For these products there is no stated Retest, Expiration or Use-by-Date Date. We recommend handling per defined conditions as printed in our product literature and website product descriptions. Products should be routinely inspected by the customer to ensure they perform as expected.
For those products, only our standard warranty of 1 year is applicable. For further information on our warranty please refer to terms and conditions of sale.
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O9389
Oltipraz
≥98% (HPLC), powder
Synonym(e):
4-Methyl-5-(2-pyrazinyl)-1,2-dithiole-3-thione, BRN 0978110, CCRIS 4048, NSC 347901, RP 35972
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| Ihnen/SKU | Verfügbarkeit | Preis |
|---|---|---|
5 mg | Warenkorb auf Verfügbarkeit prüfen | € 106,00 € 90,10 |
25 mg | Warenkorb auf Verfügbarkeit prüfen | € 428,00 € 363,80 |
Über diesen Artikel
Empirische Formel (Hill-System):
C8H6N2S3
CAS-Nummer:
Molekulargewicht:
226.34
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
264-736-6
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
protect from light
€ 90,10
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Unterstützung erhaltenassay
≥98% (HPLC)
form
powder
storage condition
protect from light
color
red
solubility
DMSO: >20 mg/mL
storage temp.
2-8°C
SMILES string
CC1=C(SSC1=S)c2cnccn2
InChI
1S/C8H6N2S3/c1-5-7(12-13-8(5)11)6-4-9-2-3-10-6/h2-4H,1H3
InChI key
CKNAQFVBEHDJQV-UHFFFAOYSA-N
General description
Oltipraz, a dithiol derivative, is a member of dithiolethiones class of organosulfur compounds. It has anti-tumor, antioxidative, anti- inflammatory and radioprotective properties. It provides protection from numerous carcinogens. Oltipraz functions as a schistosomicide.
Biochem/physiol Actions
Oltipraz is an activator of Nrf2.
Oltipraz is an activator of Nrf2. Nrf2 (NF-E2-related factor 2) is a transcription factor that binds to antioxidant response elements (AREs) and activates these genes. Oltipraz activates Nrf2 and subsequently elevates expression of the detoxification genes encoding anti-oxidant and multidrug resistance-associated proteins to mediate its chemopreventive efficacy.
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Dieser Artikel | |||
|---|---|---|---|
| form powder | form powder | form solid | form solid |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥95% (HPLC) | assay ≥98% (HPLC) |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| storage condition protect from light | storage condition protect from light | storage condition OK to freeze, protect from light | storage condition OK to freeze, protect from light |
| solubility DMSO: >20 mg/mL | solubility DMSO: 10 mg/mL, clear | solubility DMSO: 10 mg/mL | solubility DMSO: 3 mg/mL |
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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