N8130

4-Nitrophenylacetat

esterase substrate, chromogenic, ≥98% (TLC), powder or crystals

• Synonym(e): 4-Nitrophenyl-acetat
• Lineare Formel: CH₃CO₂C₆H₄NO₂
• CAS-Nummer: 830-03-5
• Molekulargewicht: 181.15
• NACRES: NA.32
• PubChem Substance ID: 24897853
• UNSPSC Code: 12352204
• EC Number: 212-593-5
• MDL number: MFCD00007326
• Beilstein/REAXYS Number: 515874

Eigenschaften

• Produktname: 4-Nitrophenylacetat, esterase substrate
• Quality Segment: 200
• assay: ≥98% (TLC)
• form: powder or crystals
• mp: 75-77 °C (lit.)
• storage temp.: −20°C
• SMILES string: CC(=O)Oc1ccc(cc1)[N+]([O-])=O
• InChI: 1S/C8H7NO4/c1-6(10)13-8-4-2-7(3-5-8)9(11)12/h2-5H,1H3
• InChI key: QAUUDNIGJSLPSX-UHFFFAOYSA-N
• Gene Information: human ... PON1(5444)

Beschreibung

General description

Chromogenic esterase substrate.

Application

4-Nitrophenyl acetate has been used:

• to evaluate esterase activity in human embryonic kidney cell line[1]
• in carbonic anhydrase inhibition assay
• to study its conversion to p-nitrophenol (p-NP) by the esterase activity of bovine serum albumin
• as a substrate to determine carboxylesterase (CES) activity in mouse liver cells[2]
• to study the advantages of bioconjugation of cross-linked enzyme aggregates (CLEAs) and magnetic iron oxide nanoparticles (MIONPs) in magnetic CLEAs matrix

Sicherheitshinweise

• pictograms: GHS03,GHS05,GHS07
• signalword: Danger
• hcodes: H272,H317,H318
• pcodes: P210 - P220 - P261 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Ox. Sol. 3 - Skin Sens. 1
• Lagerklasse: 5.1B - Oxidizing hazardous materials
• wgk: WGK 3
• flash_point_f: No data available
• flash_point_c: No data available
• ppe: Eyeshields, Gloves, type N95 (US)