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Merck

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N6377

Norharmane hydrochloride

crystalline

Synonym(e):

β-Carboline, 9H-Pyrido(3,4-b)indole

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Über diesen Artikel

Empirische Formel (Hill-System):
C11H8N2 · HCl
CAS-Nummer:
Molekulargewicht:
204.66
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:


form

crystalline

color

yellow to green

storage temp.

2-8°C

SMILES string

Cl.c1ccc2c(c1)[nH]c3cnccc23

InChI

1S/C11H8N2.ClH/c1-2-4-10-8(3-1)9-5-6-12-7-11(9)13-10;/h1-7,13H;1H

InChI key

NEECSQBLLQEFLK-UHFFFAOYSA-N

Biochem/physiol Actions

Inhibitor of indoleamine 2,3-dioxygenase (IDO).


Lagerklasse

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Monica M Arnold et al.
Neuropharmacology, 85, 293-304 (2014-06-08)
Tobacco use is the leading cause of preventable death. Although the health risks are well known, cessation rates remain low. Whereas behavioral and neuroanatomical studies on tobacco addiction conventionally use nicotine, there is evidence that other constituents, such as monoamine
Olga I Tarzi et al.
Journal of mass spectrometry : JMS, 44(2), 260-277 (2008-11-18)
The thermal stability of several commonly used crystalline matrix-assisted ultraviolet laser desorption/ionization mass spectrometry (UV-MALDI-MS) matrices, 2,5-dihydroxybenzoic acid (gentisic acid; GA), 2,4,6-trihydroxyacetophenone (THA), alpha-cyano-4-hydroxycinnamic acid (CHC), 3,5-dimethoxy-4-hydroxycinnamic acid (sinapinic acid; SA), 9H-pirido[3,4-b]indole (nor-harmane; nor-Ho), 1-methyl-9H-pirido[3,4-b]indole (harmane; Ho), perchlorate of nor-harmanonium
Rosa Busquets et al.
Molecular nutrition & food research, 53(12), 1496-1504 (2009-10-08)
Heterocyclic amines (HCAs) are potent mutagens/carcinogens to which humans are frequently exposed through the consumption of cooked meat and fish food. The effect of normal intake of HCAs and their role in the aetiology of human cancer is unknown. To