MAK100
Inosine Assay Kit
sufficient for 100 fluorometric tests
Synonym(e):
Inosine Fluorometric Assay Kit
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Alle Fotos(2)
About This Item
UNSPSC-Code:
12161503
NACRES:
NA.84
Empfohlene Produkte
Verwendung
sufficient for 100 fluorometric tests
Nachweisverfahren
fluorometric
Relevante Krankheit(en)
cardiovascular diseases; immunological diseases
Lagertemp.
−20°C
Allgemeine Beschreibung
Inosine is a purine nucleotide found at the wobble position of tRNA where it plays a role in the proper translation of mRNA at the ribosome. In addition to its role in translation, inosine also plays important roles in the immune system where is exhibits both inflammatory and anti-inflammatory effects. Inosine may be tissue protective during ischemic injury and recent reports suggest inosine may preserve cell viability during hypoxia.
Anwendung
Inosine Assay Kit has been used for the detection of inosine in the brain tissue homogenates.
Eignung
Suitable for the measurement of inosine in a variety of samples including tissue and cells
Prinzip
The Inosine Assay Kit provides a simple and direct procedure for measuring inosine in a variety of samples. Inosine concentration is determined by a coupled enzyme reaction in which inosine is converted to hypoxanthine which reacts with the substrate mix and probe, resulting in a fluorometric product (λex = 535/λem = 587 nm), proportional to the inosine present.
Lagerklassenschlüssel
10 - Combustible liquids
Flammpunkt (°F)
188.6 °F - closed cup
Flammpunkt (°C)
87 °C - closed cup
Analysenzertifikate (COA)
Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.
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Cell-subtype-specific changes in adenosine pathways in schizophrenia.
O?Donovan S M, et al.
Neuropsychopharmacology, 43, 1667?1674-1667?1674 (2018)
Sinead Marie O'Donovan et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 43(8), 1667-1674 (2018-02-28)
Prior work in animal models implicates abnormalities of adenosine metabolism in astrocytes as a possible pathophysiological mechanism underlying the symptoms of schizophrenia. In the present study, we sought to reverse-translate these findings back to the human brain in schizophrenia, focusing
Ariadna Sitjà-Bobadilla et al.
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In the animal production sector, enteritis is responsible for serious economic losses, and intestinal parasitism is a major stress factor leading to malnutrition and lowered performance and animal production efficiency. The effect of enteric parasites on the gut function of
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