M9651

Maprotilin -hydrochlorid

>99% (HPLC), powder

• Synonym(e): 9-(γ-Methylaminopropyl)-9,10-dihydro-9,10-ethanoanthracen -hydrochlorid
• Empirische Formel (Hill-System): C₂₀H₂₃N · HCl
• CAS-Nummer: 10347-81-6
• Molekulargewicht: 313.86
• NACRES: NA.77
• PubChem Substance ID: 24278576
• UNSPSC Code: 12352200
• EC Number: 233-758-8
• MDL number: MFCD00079464
• Assay: >99% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 200
• assay: >99% (HPLC)
• form: powder
• color: white
• solubility: H₂O: 50 mg/mL
• originator: Novartis
• SMILES string: Cl.CNCCCC12CCC(c3ccccc13)c4ccccc24
• InChI: 1S/C20H23N.ClH/c1-21-14-6-12-20-13-11-15(16-7-2-4-9-18(16)20)17-8-3-5-10-19(17)20;/h2-5,7-10,15,21H,6,11-14H2,1H3;1H
• InChI key: NZDMFGKECODQRY-UHFFFAOYSA-N
• Gene Information: human ... SLC6A2(6530)

Beschreibung

Application

Maprotiline hydrochloride has been used as a inhibitor of norepinephrine uptake to study its effects on arresting L3055 cell proliferation.

Biochem/physiol Actions

Maprotiline is a tetracyclic agent. It possesses inhibitory effects against the uptake of norepinephrine by nerve cells. Maprotiline exhibits anti-depressant and sedative activity.

Features and Benefits

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• Hazard Classifications: Acute Tox. 4 Oral
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves