M6875

2-Mercaptopurin

≥95%, crystalline

• Synonym(e): 2-MP, 2-Purinethiol, 2-Thiopurine
• Empirische Formel (Hill-System): C₅H₄N₄S
• CAS-Nummer: 28128-19-0
• Molekulargewicht: 152.18
• NACRES: NA.51
• PubChem Substance ID: 24897120
• UNSPSC Code: 41106305
• EC Number: 248-855-0
• MDL number: MFCD00047145
• Assay: ≥95%
• Form: crystalline
• Solubility: 1 M NH4OH: 50 mg/mL, clear to slightly hazy, yellow to brown

Eigenschaften

• Quality Segment: 100
• assay: ≥95%
• form: crystalline
• color: yellow
• solubility: 1 M NH4OH: 50 mg/mL, clear to slightly hazy, yellow to brown
• SMILES string: [H]n1cnc2cnc(S)nc12
• InChI: 1S/C5H4N4S/c10-5-6-1-3-4(9-5)8-2-7-3/h1-2H,(H2,6,7,8,9,10)
• InChI key: HDBQZGJWHMCXIL-UHFFFAOYSA-N

Beschreibung

Application

2-Mercaptopurine (2-MP), a thiopurine and analog of the anti-cancer drug 6-mercaptopurine (6-MP), has been used to study the substrate and binding specificity and kinetics of xanthine oxidase-catalyzed hydroxylation and myeloperoxidase (MPO) reactions. 2-Mercaptopurine inhibited lipopolysacharide (LPS)-dependent nitric oxide (NO) production in B cells.

Sicherheitshinweise

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H302,H318
• pcodes: P280 - P301 + P312 + P330 - P305 + P351 + P338 + P310
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves