The solubility of this product is tested in chloroform at 50 mg/mL. Solution stability has not been determined, however the acetate form is unstable in solution and should be prepared fresh. The end user would have to validate solution stability of this compound experimentally. The NIH lists the material as being soluble in ethanol, methanol, ether, and acetone. Please see the link below to review this publication:
https://pubchem.ncbi.nlm.nih.gov/compound/Medroxyprogesterone#section=Color-Form
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Wichtige Dokumente
M6013
Medroxyprogesteron
Synonym(e):
17α-Hydroxy-6α-methylprogesteron, 17a-Hydroxy-6a-methyl-4-pregnen-3,20-dion, 6-Dihydromegestrol, 6a-Methyl-5-pregnen-17a-ol-3,20-dion
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About This Item
Empirische Formel (Hill-System):
C22H32O3
CAS-Nummer:
Molekulargewicht:
344.49
Beilstein:
2510965
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
51111800
PubChem Substanz-ID:
NACRES:
NA.77
Preise und Verfügbarkeit sind derzeit nicht verfügbar.
Empfohlene Produkte
Biologische Quelle
synthetic (organic)
Assay
≥98% (HPLC)
Form
powder
Löslichkeit
chloroform: 50 mg/mL, clear, colorless to faintly yellow
Versandbedingung
ambient
Lagertemp.
room temp
SMILES String
[H][C@@]12C[C@H](C)C3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(C)=O
InChI
1S/C22H32O3/c1-13-11-16-17(20(3)8-5-15(24)12-19(13)20)6-9-21(4)18(16)7-10-22(21,25)14(2)23/h12-13,16-18,25H,5-11H2,1-4H3/t13-,16+,17-,18-,20+,21-,22-/m0/s1
InChIKey
FRQMUZJSZHZSGN-HBNHAYAOSA-N
Angaben zum Gen
rat ... Ar(24208)
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Vorsicht
Ein Großteil der Pharmakologie Literatur bezieht sich auf Medroxyprogesteronacetat als Medroxyprogesteron, diese sind jedoch nicht die selbe Substanz.
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Beschreibung
Preisangaben
Signalwort
Warning
H-Sätze
Gefahreneinstufungen
Repr. 2
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Persönliche Schutzausrüstung
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
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James Hassell et al.
Hormones and behavior, 60(2), 219-225 (2011-06-04)
Progestins and antiprogestins are widely used therapeutic agents in humans. In many cases, these are indicated for the treatment of reproductive activities. However, progesterone has widespread physiological effects including a reduction of the response to stress. We have reported that
The role of medroxyprogesterone acetate (MPA) in the treatment of renal adenocarcinoma.
M Kjaer
Cancer treatment reviews, 15(3), 195-209 (1988-09-01)
A Günzel-Apel et al.
Reproduction in domestic animals = Zuchthygiene, 47 Suppl 6, 55-60 (2013-01-04)
Progesterone profiles of individual bitches may vary considerably both between and within individuals during pregnancy and non-pregnancy. Suspected luteal deficiency is commonly purported but is difficult to evaluate in clinical cases when progesterone is supplemented because this masks the underlying
Kevin D Beck et al.
Neurobiology of learning and memory, 97(1), 148-155 (2011-12-06)
Ovarian hormones modulate acquisition processes involved in classical conditioning. Although progesterone has been indirectly implicated, its role in classical conditioning of the eyeblink response has not been directly investigated. We assessed the effects of daily dosing of progesterone or medroxyprogesterone
P C Schwallie
Contraception, 23(4), 375-386 (1981-04-01)
Data from published studies of the quantity of medroxyprogesterone acetate and/or its metabolites in the milk of lactating women receiving Depo-Provera for contraception is extrapolated into the amount of drug ingested daily by a theoretically average infant. Comparisons are made
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is there is any other solution can be used to dissolve the Medroxyprogesterone and whats the tempreture we need to use for stoarge after dissolving the Medroxyprogesterone
1 answer-
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