M1629

Medroxyprogesteron-17-Acetat

synthetic (organic), ≥97% (HPLC), synthetic progestogen, powder

• Synonym(e): 17α-Acetoxy-6α-methylprogesteron, 17α-Hydroxy-6α-methyl-4-pregnen-3,20-dion-17-acetat, 6α-Methyl-17α-acetoxyprogesteron, 6α-Methyl-17α-hydroxyprogesteron-acetat
• Empirische Formel (Hill-System): C₂₄H₃₄O₄
• CAS-Nummer: 71-58-9
• Molekulargewicht: 386.52
• NACRES: NA.77
• PubChem Substance ID: 24896674
• UNSPSC Code: 12352200
• EC Number: 200-757-9
• MDL number: MFCD00010483
• Beilstein/REAXYS Number: 2066112
• Assay: ≥97% (HPLC)
• Form: powder

Eigenschaften

• Produktname: Medroxyprogesteron-17-Acetat, ≥97% (HPLC)
• biological source: synthetic (organic)
• Quality Segment: 100
• sterility: non-sterile
• assay: ≥97% (HPLC)
• form: powder
• mp: 206-207 °C (lit.)
• solubility: chloroform: 350 mg/mL, clear, colorless
• shipped in: ambient
• storage temp.: room temp
• SMILES string: [H][C@@]12C[C@H](C)C3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@@]4(C)[C@@]2([H])CC[C@]4(OC(C)=O)C(C)=O
• InChI: 1S/C24H34O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h13-14,18-20H,6-12H2,1-5H3/t14-,18+,19-,20-,22+,23-,24-/m0/s1
• InChI key: PSGAAPLEWMOORI-PEINSRQWSA-N
• Gene Information: human ... AR(367), ESR1(2099), ESRRA(2101), NR3C1(2908), NR3C2(4306), PGR(5241) ; rat ... Ar(24208)

Beschreibung

Biochem/physiol Actions

Medroxyprogesterone 17-acetate (MPA) is a synthetic progestin used as a contraceptive, in hormone replacement therapy and for the treatment of endometriosis. It is a more potent progestin that the nonacetylated form.

Features and Benefits

This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• pictograms: GHS08
• signalword: Warning
• hcodes: H351,H413
• pcodes: P202 - P273 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Aquatic Chronic 4 - Carc. 2
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• ppe: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges