M3895

Mucin aus Rinderunterkieferdrüse

Type I-S

• Synonym(e): MUC
• CAS-Nummer: 84195-52-8
• EG-Nummer: 282-357-4
• MDL-Nummer: MFCD00131629
• UNSPSC-Code: 12352202
• NACRES: NA.61

Eigenschaften

• Biologische Quelle: bovine submaxillary glands
• Qualitätsniveau: 200
• Typ: Type I-S
• Form: powder
• Zusammensetzung: Bound sialic acids, 9-24%
• Methode(n): electrophoresis: suitable
• UniProt-Hinterlegungsnummer: P98091
• Lagertemp.: −20°C
• Angaben zum Gen: cow ... BSM(286841)

Beschreibung

Allgemeine Beschreibung

Mucin from bovine submaxillary glands is encoded by two bovine submaxillary BSM genes.[1] It is present in the saliva and interacts with air and food. Mucin comprises three major domains namely N- and C terminal and the glycosylated proline, threonine and serine (PTS domain) central domain.[2] The sialic acid contributes to 30% of the molecular weight of mucin.[2] The central domain has many tandem repeats.[1]

Anwendung

Mucin from bovine submaxillary glands has been used:

• in the quantification of mucin[3]
• as a component of artificial tear solution[4]
• as a substrate for recombinant sialidase Gardnerella vaginalis[5]
• to investigate a galactose-specific lectin from the red marine alga Ptilota filicina
• to study the characterization of a unique mucin-like glycoprotein secreted by a human endometrial adenocarcinoma cell line (Ishikawa)

Biochem./physiol. Wirkung

Albuminoid substance in mucus which gives it its ropy consistency

Bovine submaxillary mucin (BSM) is thermally stable up to 85°C.[6] The terminal domain regions are key for the adsorption functionality of mucin.[7]

Verlinkung

Similar to M 4503, but produced by Sigma.

Substrate

Neuraminidase substrate.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)