Direkt zum Inhalt
Merck

M003

Sigma-Aldrich

R-(−)-Deprenyl -hydrochlorid

powder, ≥98% (HPLC)

Synonym(e):

(R)-(−)-N,α-Dimethyl-N-(2-propinyl)-phenethylamin -hydrochlorid, (R)-(−)-N-α-Dimethyl-N-2-propinyl-benzolethanamin -hydrochlorid, Selegilin -hydrochlorid

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise

Größe auswählen

250 MG
€ 110,00
1 G
€ 309,00

€ 110,00


Voraussichtliches Versanddatum16. April 2025


Bulk-Bestellung anfordern

Größe auswählen

Ansicht ändern
250 MG
€ 110,00
1 G
€ 309,00

About This Item

Empirische Formel (Hill-System):
C13H17N · HCl
CAS-Nummer:
Molekulargewicht:
223.74
MDL-Nummer:
UNSPSC-Code:
12352200
PubChem Substanz-ID:
NACRES:
NA.77

€ 110,00


Voraussichtliches Versanddatum16. April 2025


Bulk-Bestellung anfordern

Qualitätsniveau

Assay

≥98% (HPLC)

Form

powder

Optische Aktivität

[α]25/D −10.8°, c = 6.48 in H2O(lit.)

Farbe

white

mp (Schmelzpunkt)

141-142  °C

Löslichkeit

H2O: >10 mg/mL

Ersteller

Sanofi Aventis

SMILES String

Cl[H].C[C@H](Cc1ccccc1)N(C)CC#C

InChI

1S/C13H17N.ClH/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13;/h1,5-9,12H,10-11H2,2-3H3;1H/t12-;/m1./s1

InChIKey

IYETZZCWLLUHIJ-UTONKHPSSA-N

Angaben zum Gen

human ... MAOB(4129)

Suchen Sie nach ähnlichen Produkten? Aufrufen Leitfaden zum Produktvergleich

Biochem./physiol. Wirkung

Selektiver MAO-B Hemmer; Antiparkinsonmittel.

Leistungsmerkmale und Vorteile

This compound is featured on the Dopamine and Norepinephrine Metabolism and Histamine Synthesis and Metabolism pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Piktogramme

Exclamation mark

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Acute Tox. 4 Oral - STOT SE 3

Zielorgane

Central nervous system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

Die passende Version wird nicht angezeigt?

Wenn Sie eine bestimmte Version benötigen, können Sie anhand der Lot- oder Chargennummer nach einem spezifischen Zertifikat suchen.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Michael M Monaghan et al.
Neuro-degenerative diseases, 7(1-3), 153-159 (2010-03-04)
Parkinson's disease (PD) is a progressive neurodegenerative condition characterized by an increasing loss of dopaminergic neurons resulting in motor dysfunction. However, cognitive impairments in PD patients are a common clinical feature that has gained increased attention. The purpose of the
Dominic Lomiwes et al.
Journal of agricultural and food chemistry, 72(30), 16777-16789 (2024-07-19)
Previous clinical studies indicate that monoamine oxidase-B (MAO-B) inhibition by blackcurrants must be predominantly attributed to bioactives other than anthocyanins. In this natural products discovery study, MAO-A/B inhibitory phytochemicals were isolated from blackcurrants, and a double-blind crossover study investigated the
Olivia J Kalimon et al.
Experimental neurology, 363, 114356-114356 (2023-02-26)
Monoamine oxidase (MAO) is an enzyme located on the outer mitochondrial membrane that metabolizes amine substrates like serotonin, norepinephrine and dopamine. MAO inhibitors (MAOIs) are frequently utilized to treat disorders such as major depression or Parkinson's disease (PD), though their
Edward E Putnins et al.
Frontiers in pharmacology, 12, 741460-741460 (2021-12-07)
Mucosal epithelial cell integrity is an important component of innate immunity and it protects the host from an environment rich in microorganisms. Virulence factors from Gram-negative bacteria [e.g. lipopolysaccharide (LPS)] induce significant pro-inflammatory cytokine expression. Monoamine oxidase (MAO) inhibitors reduce
Hojae Lee et al.
Nature neuroscience, 24(12), 1673-1685 (2021-11-17)
Amyotrophic lateral sclerosis (ALS) is a devastating disorder in which motor neurons degenerate, the causes of which remain unclear. In particular, the basis for selective vulnerability of spinal motor neurons (sMNs) and resistance of ocular motor neurons to degeneration in

Questions

Reviews

No rating value

Active Filters

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.