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M003
R-(−)-Deprenyl -hydrochlorid
≥98% (HPLC), MAO-B inhibitor, powder
Synonym(e):
(R)-(−)-N,α-Dimethyl-N-(2-propinyl)-phenethylamin -hydrochlorid, (R)-(−)-N-α-Dimethyl-N-2-propinyl-benzolethanamin -hydrochlorid, Selegilin -hydrochlorid
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| Packungsgröße | SKU | Verfügbarkeit | Preis |
|---|---|---|---|
| 250 mg | Warenkorb auf Verfügbarkeit prüfen | € 95,80 | |
| 1 g | Warenkorb auf Verfügbarkeit prüfen | € 291,00 |
Über diesen Artikel
Empirische Formel (Hill-System):
C13H17N · HCl
CAS-Nummer:
Molekulargewicht:
223.74
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
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Unterstützung erhaltenProduktname
R-(−)-Deprenyl -hydrochlorid, powder, ≥98% (HPLC)
Quality Level
assay
≥98% (HPLC)
form
powder
optical activity
[α]25/D −10.8°, c = 6.48 in H2O(lit.)
color
white
mp
141-142 °C
solubility
H2O: >10 mg/mL
originator
Sanofi Aventis
SMILES string
Cl[H].C[C@H](Cc1ccccc1)N(C)CC#C
Verwandte Kategorien
Biochem/physiol Actions
Selektiver MAO-B Hemmer; Antiparkinsonmittel.
Features and Benefits
This compound is featured on the Dopamine and Norepinephrine Metabolism and Histamine Synthesis and Metabolism pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral - STOT SE 3
target_organs
Central nervous system
Lagerklasse
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Parkinson's disease (PD) is a progressive neurodegenerative condition characterized by an increasing loss of dopaminergic neurons resulting in motor dysfunction. However, cognitive impairments in PD patients are a common clinical feature that has gained increased attention. The purpose of the
Olivia J Kalimon et al.
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Mucosal epithelial cell integrity is an important component of innate immunity and it protects the host from an environment rich in microorganisms. Virulence factors from Gram-negative bacteria [e.g. lipopolysaccharide (LPS)] induce significant pro-inflammatory cytokine expression. Monoamine oxidase (MAO) inhibitors reduce
J W Tetrud et al.
Science (New York, N.Y.), 245(4917), 519-522 (1989-08-04)
The effects of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine), a neurotoxin that produces the symptoms of Parkinson's disease, can be fully prevented in experimental animals by inhibiting monoamine oxidase B. On the basis of this observation, a double-blind, placebo-controlled study in patients with early
Global Trade Item Number
| SKU | GTIN |
|---|---|
| M003-250MG | 04061835557653 |
| M003-1G | 04061835512720 |
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