Peroxisome proliferator-activated receptor alpha (PPAR alpha) mediates the effects of foreign chemical peroxisome proliferators on liver and kidney, including the induction of peroxisomal, mitochondrial, and microsomal enzymes involved in beta-oxidation of fatty acids. However, the role of this receptor in
Journal of the American Society of Nephrology : JASN, 13(3), 611-620 (2002-02-22)
Natural activators of peroxisome proliferator-activated receptors (PPAR) are lipid metabolites, including those produced by phospholipases A(2) (PLA(2)). In glomerular mesangial cells, the secreted group IIA PLA(2) (sPLA(2)-IIA), which is thought to be a crucial factor in pathologic processes in the
Common structural requirements for peroxisome proliferation by tetrazole and carboxylic acid-containing compounds.
P I Eacho et al.
Annals of the New York Academy of Sciences, 804, 387-402 (1996-12-27)
Critical care medicine, 23(2), 231-237 (1995-02-01)
Both thromboxane A2 and peptide leukotrienes D4/E4 have been implicated in the pathophysiology of circulatory shock. In the present study, we evaluated the effect of thromboxane A2 and leukotriene D4/E4 receptor antagonism in circulatory shock. Prospective, randomized, controlled trial. Research
European journal of obstetrics, gynecology, and reproductive biology, 77(1), 61-65 (1998-04-29)
The aim of this work was to study the action of leukotrienes on the growth of human mammary cancer cells MCF-7. The growth of the cells was measured by incorporation of 3H-thymidine. The action of leukotriene (LT)B4, LTD4, LTC4, LTE4
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