K1750

α-Ketoglutarsäure

≥98.5% (NaOH, titration)

• Synonym(e): 2-Oxo-glutarsäure, 2-Oxopentandisäure
• Lineare Formel: HOOCCH₂CH₂COCOOH
• CAS-Nummer: 328-50-7
• Molekulargewicht: 146.10
• UNSPSC Code: 12352204
• NACRES: NA.32
• PubChem Substance ID: 57654314
• EC Number: 206-330-3
• Beilstein/REAXYS Number: 1705689
• MDL number: MFCD00004165

Eigenschaften

• Quality Segment: 200
• assay: ≥98.5% (NaOH, titration)
• form: powder
• solubility: water: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow
• storage temp.: 2-8°C
• SMILES string: OC(=O)CCC(=O)C(O)=O
• InChI: 1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)
• InChI key: KPGXRSRHYNQIFN-UHFFFAOYSA-N

Beschreibung

General description

α-Ketoglutaric acid (α-KG) is produced in the tricarboxylic acid cycle.[1]

Application

α-Ketoglutaric acid (α-KG) has been used:

• to study its effects on swine fecal microflora in an in vitro fermentation system[2]
• to study its effects on the activation of CD8⁺ T-cells[3]
• as a substrate in glutamate oxaloacetate transaminase (GOT2) mitochondrial lysate assay[4]

Biochem/physiol Actions

α-Ketoglutaric acid (α-KG) has a wide range of applications in the animal feed, food, pharmaceutical and fine chemistry industries.[1]

Sicherheitshinweise

• pictograms: GHS05
• signalword: Danger
• hcodes: H318
• pcodes: P280 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1
• Lagerklasse: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves