I8659

Anti-Interferon-γ antibody produced in goat

affinity isolated antibody, lyophilized powder

• Synonym(e): Anti-IFN-γ
• UNSPSC Code: 51111800
• NACRES: NA.41
• MDL number: MFCD00162308
• Conjugate: unconjugated
• Clone: polyclonal
• Application: IHC, Neutral, WB
• Citations: 6

Eigenschaften

• biological source: goat
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: lyophilized powder
• species reactivity: human
• technique(s): immunohistochemistry: 5-15 μg/mL, neutralization: suitable, western blot: 0.1-0.2 μg/mL
• UniProt accession no.: P01579
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... IFNG(3458)

Beschreibung

General description

IFNγR2. There are many pathways that are mediated by IFN-γ binding such as JAK/STAT1, AP-1, NF-κB, STAT3 and STAT5. IFN-γ is pleotropic and performs various functions related to immune response, inflammation, differentiation and activation of T cells, cell cycle and apoptosis. The most studied function of IFN-γ is priming the antigen presenting cells by upregulating major histocompatibility (MHC) Class I molecules. IFN-γ has clinical applications in autoimmune diseases (rheumatoid arthritis), multiple sclerosis, cancer, HIV and fungal infections
Anti-Interferon-γ recognizes human Interferon-γ.

Immunogen

purified, E. coli-derived recombinant human interferon γ.

Application

Anti-interferon-γ antibody may be used for immunoblotting at a working concentration of 0.1-0.2 μg/ml. For immunohistochemistry the recommended concentration is 5-15 μg/ml. The antibody has been used for immunohistochemistry of human cervical spinal cord sections using a concentration of 15 μg/ml. The antibody is suitable for neutralization reactions.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklasse: 13 - Non Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)