I7026

Anti-Insulin-like Growth Factor Binding Protein-4 antibody produced in goat

affinity isolated antibody, lyophilized powder

• Synonym(e): Anti-IGFBP-4
• MDL-Nummer: MFCD01633492
• UNSPSC-Code: 51111800

Eigenschaften

• Biologische Quelle: goat
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: lyophilized powder
• Speziesreaktivität: human
• Methode(n): indirect ELISA: 0.5-1.0 μg/mL; neutralization: suitable; western blot: 0.1-0.2 μg/mL
• UniProt-Hinterlegungsnummer: P22692
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... IGFBP4(3487)

Beschreibung

Allgemeine Beschreibung

Insulin-like growth factor binding protein-4 (IGFBP-4) is a 26kD (approx.) protein expressed highly in non-paranchymal cells of the liver. IGFBP-4 is also expressed in spleen, liver, lung, kidney, adrenal, testis, heart, brain cortex, stomach and hypothalamus. It has a pivotal role in protecting cells from overstimulation caused by IGFs or towards activating the alternate transmembrane signaling pathways that are inhibited by IGF exposure. Anti-Insulin-like Growth Factor Binding Protein 4(IGFBP-4) antibody can be used in western blotting. Goat anti-IGFBP-4 antibody reacts specifically with recombinant human IGFBP-4. The product has shown no cross-reactivity for recombinant human IGFBP-1, recombinant human IGFBP-2, recombinant human IGFBP-3, recombinant human IGFBP-5 and recombinant human IGFBP-6.

Spezifität

By immunoblotting and ELISA, the antibody show no cross-reactivity with recombinant human IGFBP-2, recombinant human IGFBP-3, recombinant human IGFBP-1, recombinant human IGFBP-5, and recombinant human IGFBP-6.

Immunogen

purified, NSO-derived, recombinant human insulin-like growth factor binding protein 4.

Anwendung

Anti-Insulin-like Growth Factor Binding Protein-4(IGFBP-4) antibody can be used in neutralization and indirect ELISA.

Physikalische Form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 5% trehalose.