I5161

Jodacetamid

Name: Jodacetamid
Brand: SIGMA

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Lineare Formel:

ICH₂CONH₂

CAS-Nummer:

144-48-9

Molekulargewicht:

184.96

EC Number:

205-630-1

UNSPSC Code:

12352202

NACRES:

NA.21

Beilstein/REAXYS Number:

1739080

MDL number:

MFCD00008028

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Unterstützung erhalten

biological source

synthetic

Quality Level

400

assay

≥99% (NMR)

form

powder

mp

92-95 °C (lit.)

solubility

H₂O: 0.5 M, clear, colorless

suitability

suitable for manufacturing use

storage temp.

2-8°C

SMILES string

NC(=O)CI

InChI

1S/C2H4INO/c3-1-2(4)5/h1H2,(H2,4,5)

InChI key

PGLTVOMIXTUURA-UHFFFAOYSA-N

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Dieser Artikel	A3221	I6125	I1149
SAFC I5161 Iodoacetamide	Sigma-Aldrich A3221 Iodoacetamide	Sigma-Aldrich I6125 Iodoacetamide	Sigma-Aldrich I1149 Iodoacetamide
form powder	form powder	form crystalline	form powder
biological source synthetic	biological source synthetic (organic)	biological source synthetic (organic)	biological source synthetic (organic)
assay ≥99% (NMR)	assay ≥99% (HPLC)	assay ≥99% (NMR)	assay ≥99% (NMR)
suitability suitable for manufacturing use	suitability suitable for LC-MS	suitability -	suitability -
mp 92-95 °C (lit.)	mp 92-95 °C (lit.)	mp 92-95 °C (lit.)	mp 92-95 °C (lit.)
solubility H₂O: 0.5 M, clear, colorless	solubility H₂O: soluble 50 mg/mL, clear, colorless to faintly yellow	solubility H₂O: soluble 0.5 M, clear, colorless	solubility H₂O: 0.5 M, clear, colorless

General description

Our SAFC^® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

Biochem/physiol Actions

Iodacetamid dient als Alkylierungsreagens für Cysteinreste bei der Peptidsequenzierung. Es ist ein irreversibler Inhibitor von Enzymen mit Cystein im aktiven Zentrum. Mit Histidinresten reagiert es sehr viel langsamer, aber diese Aktivität ist für die Hemmung der Ribonuklease verantwortlich.

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

GHS06,GHS08

signalword

Danger

hcodes

H301,H317,H334,H413

pcodes

P261 - P264 - P273 - P280 - P301 + P310 - P302 + P352

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 4 - Resp. Sens. 1 - Skin Sens. 1

Lagerklasse

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable

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Global Trade Item Number

SKU	GTIN
I5161-10KG	04065267543420
I5161-100G	04061832608532
I5161-25G	04061832608549

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