HT5012

Formalinlösung, neutral gepuffert, 10 %

case of 24 × 60 mL, histological tissue fixative

• Synonym(e): 10% NBF, 10% Neutral Buffered Formalin, Formaldehyde, Methanal
• UNSPSC Code: 12352114
• PubChem Substance ID: 24895888
• NACRES: NA.47
• MDL number: MFCD00003274

Eigenschaften

• biological source: synthetic
• Quality Segment: 200
• packaging: case of 24 × 60 mL
• concentration: 10% formalin (approx. 4% formaldehyde)
• color: colorless
• pH: 6.90-7.10
• density: 1.080 g/cm³
• application(s): hematology; histology
• storage temp.: room temp
• SMILES string: [O-]#[C+H2]
• InChI: 1S/CH2O/c1-2/h1H2
• InChI key: WSFSSNUMVMOOMR-UHFFFAOYSA-N

Beschreibung

General description

10% Neutral Buffered Formalin is the most used fixative throughout the world for light microscopy. Formalin solution is the commercially obtained solution containing 37% w/w (40% w/v) of formaldehyde in water. It requires a relatively short period of fixation. It is suitable for the long-term storage of tissue. Once properly fixed, the tissue should be able to withstand the subsequent stages of tissue processing or staining.

Application

Beliebtes allgemeines histologisches Fixierungsmittel

Formalin solution (neutral buffered, 10%) has been popularly used as a general-purpose histological fixative to fix tissue samples.

• It effectively preserves the cellular and tissue morphology, maintaining the structural integrity required for microscopic examination.
• It is used for routine histological staining, providing clear and detailed images of cellular structures.[1]

Biochem/physiol Actions

Formaldehyde is both a non-coagulant and an additive fixative. Formalin fixation is thought to form cross links between the aldehydes and the proteins, creating a gel, thus retaining cellular constituents in their in vivo relationship. Formaldehyde is known to penetrate tissue quickly, but the fixation process may take a long time to form the various cross links with tissue proteins.

Features and Benefits

• 10% NBF is well-suited for large throughput laboratories.
• It requires a relatively short period of fixation.
• It can be used for the long-term storage of tissue.

Packaging

Case containers are polypropylene with white leak-proof lids and are partially prefilled with 10% NBF.

Physical form

Neutral gepufferte Lösung

Sicherheitshinweise

• pictograms: GHS08,GHS07
• signalword: Danger
• hcodes: H302 + H332,H317,H341,H350
• pcodes: P202 - P280 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Muta. 2 - Skin Sens. 1
• wgk: WGK 3
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
• Lagerklasse: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• flash_point_f: 185.0 °F
• flash_point_c: 85 °C