H5916

Human Growth Hormone

HumanKine^®, recombinant, Xeno-free, >95% (SDS-PAGE), suitable for cell culture

• Synonym(e): HGH, somatotropin
• UNSPSC Code: 12352202
• NACRES: NA.77
• Biological source: human
• Recombinant: expressed in HEK 293 cells
• Assay: ≥95% (SDS-PAGE)
• Form: lyophilized powder
• Mol wt: monomer 22 kDa (non-glycosylated)
• Impurities: <1 EU/mg

Eigenschaften

• Produktname: Human Growth Hormone human, HGH, recombinant, expressed in HEK 293 cells, HumanKine^®, suitable for cell culture
• biological source: human
• Quality Segment: 100
• recombinant: expressed in HEK 293 cells
• assay: ≥95% (SDS-PAGE)
• form: lyophilized powder
• potency: ≤0.5 ng/mL EC₅₀
• mol wt: monomer 22 kDa (non-glycosylated)
• packaging: pkg of 10 μg
• storage condition: avoid repeated freeze/thaw cycles
• technique(s): cell culture | mammalian: suitable
• impurities: <1 EU/mg
• storage temp.: −20°C

Beschreibung

General description

Recombinant human growth hormone (HGH), also known as somatotropin, is expressed in HEK 293 cells and supplied as a lyophilized protein suitable for mammalian cell culture research. HGH is a single‑chain polypeptide hormone involved in cellular growth and metabolism signaling pathways in

Application

Human Growth Hormone has been used as a supplement in mammalian cell culture research, including immune response studies and differentiation workflows involving pluripotent stem cell‑derived cell types.

Biochem/physiol Actions

Human growth hormone (HGH) is required for normal human growth and development. It increases muscle mass, promotes lipolysis, and reduces liver uptake of glucose. HGH mediates cellular responses primarily through stimulation of insulin‑like growth factor signaling pathways and has been widely studied in in vitro models of cell growth, metabolism, and differentiation.

Physical form

Lyophilized from a 0.2 μm filtered solution of 1x PBS.

Preparation Note

HumanKine, Human Growth Hormone (HGH) is expressed as a non-glycosylated monomer in human HEK 293 cells and has an apparent molecular mass of 22 kDa.

Analysis Note

The activity was determined by the dose-dependent stimulation of the proliferation of rat lymphoma line Nb2-11 cells (prolactin indicator cell line).

Legal Information

HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable