GW22790

Anti-TLR9 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

• MDL-Nummer: MFCD03456046
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: chicken
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Speziesreaktivität: rat, human, mouse
• Hersteller/Markenname: Genway 15-288-22790
• Methode(n): western blot: suitable
• NCBI-Hinterlegungsnummer: NP_059138.1
• UniProt-Hinterlegungsnummer: Q9NR96
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Angaben zum Gen: human ... TLR9(54106)

Beschreibung

Immunogen

Immunogen Sequence: GI # 8394456, sequence 311-465

Recombinant toll-like receptor 9 isoform A

Anwendung

Anti-TLR9 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem./physiol. Wirkung

Toll-like receptor 9 is a protein encoded by the TLR9 gene in humans. It is a cellular DNA-receptor and is widely expressed in breast as well as other cancers.[1] It plays an important role in the pathogenesis of systemic lupus erythematosus (SLE) and has an impact on organ involvement in SLE.[2] Expression of TLR-9 is a good indicator and helps in distinguishing cancer patients from benign and normal controls.[3] TLR9 plays a crutial role in sensing a wide range of pathogens, including bacteria, fungi and viruses. Dysregulation of its signaling may contribute to a higher risk of developing cancers.[4]

Physikalische Form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)