G0299

Protodioscin

from Dioscorea spp., ≥98% (HPLC)

• Synonym(e): Furostanol I
• Empirische Formel (Hill-System): C₅₁H₈₄O₂₂
• CAS-Nummer: 55056-80-9
• Molekulargewicht: 1049.20
• MDL number: MFCD03427682
• UNSPSC Code: 12352212
• NACRES: NA.25

Eigenschaften

• biological source: Dioscorea spp.
• Quality Segment: 200
• assay: ≥98% (HPLC)
• form: powder
• application(s): metabolomics; vitamins, nutraceuticals, and natural products
• storage temp.: 2-8°C
• SMILES string: O1[C@H]([C@@H]([C@@H]([C@H]([C@@H]1C)O)O)O)O[C@H]2[C@@H](O[C@@H]([C@H]([C@@H]2O)O[C@@H]9O[C@H]([C@@H]([C@H]([C@H]9O)O)O)C)CO)O[C@H]3CC[C@@]4([C@@H]5[C@H]([C@H]6[C@@]([C@@H]7[C@@H](O[C@]([C@H]7C)(O)CC[C@H](CO[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)CO)C)C6)
• InChI: 1S/C51H84O22/c1-20(19-65-45-39(60)38(59)35(56)30(17-52)69-45)9-14-51(64)21(2)32-29(73-51)16-28-26-8-7-24-15-25(10-12-49(24,5)27(26)11-13-50(28,32)6)68-48-44(72-47-41(62)37(58)34(55)23(4)67-47)42(63)43(31(18-53)70-48)71-46-40(61)36(57)33(54)22(3)66-46/h7,20-23,25-48,52-64H,8-19H2,1-6H3/t20-,21+,22+,23+,25+,26-,27+,28+,29+,30-,31-,32+,33+,34+,35-,36-,37-,38+,39-,40-,41-,42+,43-,44-,45-,46+,47+,48-,49+,50+,51-/m1/s1
• InChI key: LVTJOONKWUXEFR-UEZXSUPNSA-N

Beschreibung

General description

Protodioscin is a steroidal saponin found in a variety of plant species. It consists of aglycone and glycone moieties and occurs as an active ingredient of the herbal aphrodisiac Tribulus terrestris used in traditional Chinese and Indian medicine.

Application

Protodioscin has been used to study the inhibitory effect of fenugreek and quinoa extracts on the activity of α-amylase and pancreatic lipase under in vitro traditional conditions. It has also been used as a standard in the study to carry out the structural characterization of the steroidal saponins extracted from Smilax trinervula.

Biochem/physiol Actions

Protodioscin shows a notable inhibitory effect on digestive enzymes such as α-amylase and pancreatic lipase. It is posited to increase the levels of testosterone, luteinizing hormone, dehydroepiandrosterone, dihydrotestosterone, and dehydroepiandrosterone sulfate along with improving libido and spermatogenesis in humans and animals. It exhibits anti-tumor activity especially against leukemia, colon cancer, and prostate cancer.

Saponin phytochemical found in asparagus. Cardioprotective and anti-hyperlipidemic agent. Cytotoxic effect against human cancer cell lines.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable