D9069

N-Desmethyltamoxifen HCl

≥98% (HPLC), solid

• Synonym(e): (Z)-2-(p-(1,2-Diphenyl-1-butenyl)phenoxy)-N-methylethylamine, ICI 55,548
• Empirische Formel (Hill-System): C₂₅H₂₇NO·HCl
• CAS-Nummer: 15917-65-4
• Molekulargewicht: 393.95
• NACRES: NA.77
• PubChem Substance ID: 329798889
• UNSPSC Code: 12352203
• MDL number: MFCD03423594
• Assay: ≥98% (HPLC)
• Form: solid
• Storage condition: desiccated

Eigenschaften

• sterility: non-sterile
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: solid
• storage condition: desiccated
• technique(s): inhibition assay: suitable
• solubility: DMSO: ≥20 mg/mL
• shipped in: ambient
• storage temp.: room temp
• SMILES string: Cl.CC\C(c1ccccc1)=C(/c2ccccc2)c3ccc(OCCNC)cc3
• InChI: 1S/C25H27NO.ClH/c1-3-24(20-10-6-4-7-11-20)25(21-12-8-5-9-13-21)22-14-16-23(17-15-22)27-19-18-26-2;/h4-17,26H,3,18-19H2,1-2H3;1H/b25-24-;
• InChI key: GMLHJWZEYLTNJW-BJFQDICYSA-N

Beschreibung

Application

N-Desmethyltamoxifen HCl has been used as an internal standard in high-performance liquid chromatography (HPLC) for the quantification of metabolites from NG2 cell-derived astrocytes.

Biochem/physiol Actions

N-Desmethyltamoxifen HCl is the primary metabolite of tamoxifen. N-Desmethyltamoxifen HCl is an estrogen response modifer and protein kinase C inhibitor.

Features and Benefits

This compound is featured on the Nuclear Receptors (Steroids) and PKC pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• pictograms: GHS08,GHS09
• signalword: Danger
• hcodes: H350,H360,H410
• pcodes: P202 - P273 - P280 - P308 + P313 - P391 - P405
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Repr. 1B
• Lagerklasse: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves, type P2 (EN 143) respirator cartridges