D7159

2′,3′-Dideoxycytidine 5′-triphosphate sodium salt

≥90% (HPLC)

• Synonym(e): ddCTP
• Empirische Formel (Hill-System): C₉H₁₆N₃O₁₂P₃
• CAS-Nummer: 132619-66-0
• Molekulargewicht: 451.16
• UNSPSC Code: 12352202
• PubChem Substance ID: 24894086
• MDL number: MFCD00717536

Eigenschaften

• Produktname: 2′,3′-Dideoxycytidine 5′-triphosphate sodium salt, ≥90% (HPLC)
• InChI: 1S/C9H16N3O12P3.Na/c10-7-3-4-12(9(13)11-7)8-2-1-6(22-8)5-21-26(17,18)24-27(19,20)23-25(14,15)16;/h3-4,6,8H,1-2,5H2,(H,17,18)(H,19,20)(H2,10,11,13)(H2,14,15,16);/q;+1/p-1/t6-,8+;/m0./s1
• SMILES string: [Na+].NC1=NC(=O)N(C=C1)[C@H]2CC[C@@H](COP([O-])(=O)OP(O)(=O)OP(O)(O)=O)O2
• InChI key: LOOMQRBEBYCFPP-QDOHZIMISA-M
• biological source: synthetic (organic)
• assay: ≥90% (HPLC)
• form: powder
• solubility: water: 1 mg/mL, clear, colorless
• storage temp.: −20°C

Beschreibung

Application

Complexes of ddCTP with DNA polymerase β were studied by x-ray crystallography, with implications for inhibitory activity against HIV reverse transcriptase.

Biochem/physiol Actions

Inhibitor of DNA polymerase I-catalyzed chain elongation.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)