COV434

7071909, human ovary, Polygonal & fusiform

• Synonym(e): COV-434 Cells
• UNSPSC-Code: 41106514

Eigenschaften

• product name: COV434, 07071909
• Biologische Quelle: human ovary
• Wachstumsmodus: Adherent
• Karyotyp: Modal chromosome no. 47 (46 - 47)
• Morphologie: Polygonal & fusiform
• Produkte: Not specified
• Rezeptoren: Not specified
• Methode(n): cell culture | mammalian: suitable
• Relevante Krankheit(en): cancer
• Versandbedingung: dry ice
• Lagertemp.: −196°C

Beschreibung

Ursprung der Zelllinie

Human ovarian granulosa tumour

Beschreibung der Zelllinie

Human ovarian granulosa tumour cell line established from a solid primary tumour.

Anwendung

COV434 has been used to study:

• the effect of 17β-estradiol on granulosa cell tumor growth, migration and invasion
• if mutant p53 (inactivatible R248Q hotspot mutation) works as a cancer-specific drug target
• the expression of TLR (toll-like receptor) and its function in the cell line

Nährmedium

DMEM + 2mM Glutamine + 10% Foetal Bovine Serum (FBS)

Subkultur-Routine

Split confluent cultures 1:2 to 1:5 i.e. seeding at 2-4x10,000 cells/cm² using trypsin/EDTA; 5% CO₂; 37°C.

Sonstige Hinweise

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