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C9749

CBiPES hydrochloride

≥98% (HPLC)

Synonym(s):

N-(4′-cyano[1,1′-biphenyl]-3-yl)-N-(3-pyridinylmethyl)-ethanesulfonamide hydrochloride

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Size/SKUAvailabilityPrice
25 mg

Estimated to ship onMay 26, 2026fromMILWAUKEE

$592.00

About This Item

Empirical Formula (Hill Notation):
C21H19N3O2S · HCl
CAS Number:
Molecular Weight:
413.92
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated

$592.00


Estimated to ship onMay 26, 2026Details


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Quality Segment

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

off-white to light brown

solubility

DMSO: >20 mg/mL

originator

Eli Lilly

storage temp.

2-8°C

SMILES string

[S](=O)(=O)(N(Cc3cnccc3)c1cc(ccc1)c2ccc(cc2)C#N)CC.Cl

InChI

1S/C21H19N3O2S.ClH/c1-2-27(25,26)24(16-18-5-4-12-23-15-18)21-7-3-6-20(13-21)19-10-8-17(14-22)9-11-19;/h3-13,15H,2,16H2,1H3;1H

InChI key

QKUHSVQWWZBAKM-UHFFFAOYSA-N

Biochem/physiol Actions

CBiPES is a positive allosteric modulator of the mGlu2 receptor.
CBiPES is a positive allosteric modulator of the mGlu2 receptor. CBiPES attenuates stress-induced hyperthermia and blocks the hyperlocomotor effects of PCP in murine models. In rat brain, CBiPES attenuates ketamine-induced increase in extracellular histamine concentration. This compound is a sulfonamide, different chemical class from other mGlu2R agonists in the Sigma catalog.

Features and Benefits

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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This Item
SML0988SML0853SML0235
assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage condition

desiccated

storage condition

-

storage condition

-

storage condition

-

solubility

DMSO: >20 mg/mL

solubility

DMSO: 20 mg/mL, clear

solubility

H2O: 1 mg/mL, clear (warmed)

solubility

DMSO: ≥5 mg/mL at warmed to 60 °C


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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