C6491

Chrysomycin B

≥98% (HPLC), solid

• Empirische Formel (Hill-System): C₂₇H₂₈O₉
• CAS-Nummer: 83852-56-6
• Molekulargewicht: 496.51
• NACRES: NA.77
• PubChem Substance ID: 24892870
• UNSPSC Code: 12352200
• MDL number: MFCD07370132

Eigenschaften

• InChI: 1S/C27H28O9/c1-11-8-15-19(17(9-11)33-4)14-10-18(34-5)21-16(28)7-6-13(20(21)22(14)36-26(15)31)23-25(30)27(3,32)24(29)12(2)35-23/h6-10,12,23-25,28-30,32H,1-5H3/t12-,23+,24+,25+,27-/m1/s1
• SMILES string: COc1cc(C)cc2C(=O)Oc3c(cc(OC)c4c(O)ccc([C@@H]5O[C@H](C)[C@H](O)[C@@](C)(O)[C@H]5O)c34)-c12
• InChI key: BJPYMDSMDBCKEP-QSMCFSHASA-N
• assay: ≥98% (HPLC)
• form: solid
• solubility: DMF: soluble, DMSO: soluble, ethanol: moderately soluble, methanol: moderately soluble
• antibiotic activity spectrum: neoplastics
• mode of action: enzyme | inhibits
• storage temp.: 2-8°C

Beschreibung

Biochem/physiol Actions

Antibiotic from Streptomyces sp. Inhibits the catalytic activity of human topoisomerase II.

Antibiotic from Streptomyces sp. Inhibits the catalytic activity of human topoisomerase II. Exhibits antitumor activity against human cell lines K562, HT29, MCF7, PC6, and MKN28.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)