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C3305

Sigma-Aldrich

Carbacyclin

≥90% (HPLC)

Synonym(e):

6a-Carba-prostaglandin I2, Carbocyclic PGI2

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About This Item

Empirische Formel (Hill-System):
C21H34O4
CAS-Nummer:
69552-46-1
Molekulargewicht:
350.49
MDL-Nummer:
MFCD00210824
UNSPSC-Code:
12352211
PubChem Substanz-ID:
24892602

Assay

≥90% (HPLC)

Lagertemp.

−20°C

SMILES String

[H][C@]12C[C@@H](O)[C@H](\C=C\[C@@H](O)CCCCC)[C@@]1([H])CC(\C2)=C\CCCC(O)=O

InChI

1S/C21H34O4/c1-2-3-4-8-17(22)10-11-18-19-13-15(7-5-6-9-21(24)25)12-16(19)14-20(18)23/h7,10-11,16-20,22-23H,2-6,8-9,12-14H2,1H3,(H,24,25)/b11-10+,15-7+/t16-,17-,18+,19-,20+/m0/s1

InChIKey

XZFRIPGNUQRGPI-WBQKLGIQSA-N

Angaben zum Gen

human ... PPARA(5465) , PPARD(5467) , PPARG(5468)

Lagerklassenschlüssel

13 - Non Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
108K1386
120M1748
056K1562
036K1444
104H0870

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Die Dokumentenbibliothek aufrufen

M J Mason et al.
The Journal of physiology, 533(Pt 1), 175-183 (2001-05-15)
Using simultaneous whole-cell patch-clamp and fluorescence measurements of [Ca2+]i in rat megakaryocytes we have investigated the requirement for functional inositol 1,4,5-trisphosphate (IP3) receptors in Ca2+ release induced by membrane depolarization during agonist stimulation. Voltage-dependent Ca2+ release was observed during application
Tadashi Kuroda et al.
Journal of molecular and cellular cardiology, 43(1), 54-62 (2007-06-02)
Prostacyclin (PGI2) and its analogues exert cardioprotective effects via the rhodopsin type membrane PGI2 receptor, IP. Peroxisome proliferator-activated receptor (PPAR) delta is a nuclear receptor abundantly expressed in cardiomyocytes and plays a pivotal role in maintaining constitutive mitochondrial fatty acid
K Noguchi et al.
Oral microbiology and immunology, 15(5), 299-304 (2001-01-12)
In the present study, we examined whether prostaglandin (PG) E2 and PGI2 regulated intercellular adhesion molecule-1 (ICAM-1) expression in human oral gingival epithelial cells stimulated with tumor necrosis factor alpha (TNF alpha). TNF alpha potently induced ICAM-1 expression in a
Mikhail Kim et al.
The Journal of organic chemistry, 71(12), 4642-4650 (2006-06-06)
A fully stereocontrolled synthesis of 3-oxacarbacyclin (3) and a formal synthesis of carbacyclin (2) are described. The syntheses are based on the conjugate addition-azoalkene-asymmetric olefination strategy. Its key features are (1) the stereoselective establishment of the complete omega-side chain of
A C Maurin et al.
Calcified tissue international, 76(5), 385-392 (2005-05-04)
As previously reported, the age-related association between bone loss and increased marrow adipose volume may involve inhibitory effects of polyunsaturated fatty acids (PUFAs) potentially released by medullary adipocytes on osteoblastic proliferation and cell cycle progression. Because PUFAs have been reported
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