C2648

Cholesterol 5β,6β-epoxide

≥98%

• Synonym(e): 5β,6β-Epoxycholestan-3β-ol
• Empirische Formel (Hill-System): C₂₇H₄₆O₂
• CAS-Nummer: 4025-59-6
• Molekulargewicht: 402.65
• MDL-Nummer: MFCD00201258
• UNSPSC-Code: 12352211
• PubChem Substanz-ID: 24892511
• NACRES: NA.28

Eigenschaften

• Assay: ≥98%
• Form: powder
• Funktionelle Gruppe: epoxy
• Versandbedingung: ambient
• Lagertemp.: room temp
• SMILES String: [H][C@@]12[C@]([C@](CC[C@H](O)C3)(C)[C@]3(O4)[C@H]4C2)([H])CC[C@@]5(C)[C@@]1([H])CC[C@]5([H])[C@]([H])(C)CCCC(C)C
• InChI: 1S/C27H46O2/c1-17(2)7-6-8-18(3)21-9-10-22-20-15-24-27(29-24)16-19(28)11-14-26(27,5)23(20)12-13-25(21,22)4/h17-24,28H,6-16H2,1-5H3
• InChIKey: PRYIJAGAEJZDBO-UHFFFAOYSA-N

Beschreibung

Anwendung

Cholesterol 5β,6β-epoxide was used to treat PC12 cells or HepG2 and Caco-2 cells[1] to study the effects of cholesterol oxidation.[2]

Biochem./physiol. Wirkung

Cholesterol 5β,6β-epoxide is an oxysterol produced as an oxidation product of cholesterol. Oxysterols are cytotoxic and induce death in monocytes, smooth muscle cells and endothelial cells. The mechanism of apoptosis induced by oxysterols may involve caspases or DNA fragmentation.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Faceshields, Gloves