C1240

Chlormethiazole hydrochloride

≥98% (HPLC), GABAA agonist, powder

• Synonym(e): 4-methyl-5-(β-chloroethyl)thiazole hydrochloride, 5-(2-Chloroethyl)-4-methylthiazole hydrochloride, Clomethiazole hydrochloride, Somnevrin hydrochloride
• Empirische Formel (Hill-System): C₆H₈ClNS · HCl
• CAS-Nummer: 6001-74-7
• Molekulargewicht: 198.11
• UNSPSC Code: 12352200
• PubChem Substance ID: 329774745
• NACRES: NA.77
• MDL number: MFCD00673948
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Produktname: Chlormethiazole hydrochloride, ≥98% (HPLC), powder
• description: Store desiccated
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: off-white
• solubility: H₂O: soluble >10 mg/mL
• originator: AstraZeneca
• SMILES string: Cl.Cc1ncsc1CCCl
• InChI: 1S/C6H8ClNS.ClH/c1-5-6(2-3-7)9-4-8-5;/h4H,2-3H2,1H3;1H
• InChI key: OFXYKSLKNMTBHK-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

GABA_A agonist; glycine receptor modulator.

Chlormethiazole serves as an anticonvulsant. It is useful in treating alcohol addiction and eclampsia. Chlormethiazole is also useful in treating convulsive status epilepticus. Long term administration of chlormethiazole leads to addiction to the drug.

Features and Benefits

This compound is a featured product for ADME Tox and Neuroscience research. Discover more featured ADME Tox and Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H302,H317,H318
• pcodes: P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 + P310
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Sens. 1
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves