B5150

Bacitracin Zinksalz

from Bacillus licheniformis, ~70,000 U/g

• Synonym(e): Zinc bacitracin
• Empirische Formel (Hill-System): C₆₆H₁₀₁N₁₇O₁₆SZn
• CAS-Nummer: 1405-89-6
• Molekulargewicht: 1486.07
• EG-Nummer: 215-787-8
• MDL-Nummer: MFCD00130598
• UNSPSC-Code: 51282002
• PubChem Substanz-ID: 57653938
• NACRES: NA.85

Eigenschaften

• Biologische Quelle: Bacillus licheniformis
• Form: powder
• Spezifische Aktivität: ~70,000 U/g
• mp (Schmelzpunkt): 250 °C (dec.) (lit.)
• Wirkungsspektrum von Antibiotika: Gram-positive bacteria
• Wirkungsweise: cell wall synthesis | interferes
• Lagertemp.: 2-8°C
• SMILES String: [Zn++].CCC(C)C(N)C1=NCC(S1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC([O-])=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H]2CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CC([O-])=O)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)[C@@H](Cc4ccccc4)NC(=O)[C@@H](NC(=O)[C@@H](CCCN)NC2=O)[C@@H](C)CC
• InChI: 1S/C66H103N17O16S.Zn/c1-9-35(6)52(69)66-72-32-48(100-66)63(97)80-43(26-34(4)5)59(93)75-42(22-23-50(85)86)58(92)83-53(36(7)10-2)64(98)76-40-20-15-16-25-71-55(89)46(29-49(68)84)78-62(96)47(30-51(87)88)79-61(95)45(28-39-31-70-33-73-39)77-60(94)44(27-38-18-13-12-14-19-38)81-65(99)54(37(8)11-3)82-57(91)41(21-17-24-67)74-56(40)90;/h12-14,18-19,31,33-37,40-48,52-54H,9-11,15-17,20-30,32,67,69H2,1-8H3,(H2,68,84)(H,70,73)(H,71,89)(H,74,90)(H,75,93)(H,76,98)(H,77,94)(H,78,96)(H,79,95)(H,80,97)(H,81,99)(H,82,91)(H,83,92)(H,85,86)(H,87,88);/q;+2/p-2/t35?,36-,37-,40-,41+,42+,43-,44+,45-,46-,47+,48?,52?,53-,54-;/m0./s1
• InChIKey: NKULICGUDKGGRL-FCHFGNCGSA-L

Beschreibung

Allgemeine Beschreibung

Chemical structure: peptide

Anwendung

Bacitracin zinc salt is a peptide antibiotic used to study dysruption of bacterial cell wall synthesis at the level of peptidoglycan biosynthesis and isoprenyl metabolism. It is used to study the biosynthesis of sterols and squalene.

Biochem./physiol. Wirkung

Bacitracin is a protease inhibitor. Antimicrobial spectrum: Gram-positive bacteria.
Mode of Action: Inhibits bacterial cell wall synthesis by inhibiting dephosphorylation of lipid pyrophosphate.

Sonstige Hinweise

Keep container tightly closed in a dry and well-ventilated place.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)