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Merck

B162

B-HT 920 dihydrochloride

solid, ≥98% (HPLC)

Synonym(e):

5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepine-2-amine dihydrochloride, Talipexole

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Über diesen Artikel

Empirische Formel (Hill-System):
C10H15N3S · 2HCl
CAS-Nummer:
36085-73-1
Molekulargewicht:
282.23
UNSPSC Code:
12352202
PubChem Substance ID:
24891601
MDL number:
MFCD00274573

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Produktname

B-HT 920 dihydrochloride, solid, ≥98% (HPLC)

InChI

1S/C10H15N3S.2ClH/c1-2-5-13-6-3-8-9(4-7-13)14-10(11)12-8;;/h2H,1,3-7H2,(H2,11,12);2*1H

SMILES string

Cl.Cl.Nc1nc2CCN(CCc2s1)CC=C

InChI key

DPQAXNSOFFYKDS-UHFFFAOYSA-N

assay

≥98% (HPLC)

form

solid

color

off-white

solubility

H2O: >20 mg/mL

Gene Information

rat ... Drd2(24318)

Biochem/physiol Actions

α2-adrenoceptor agonist; D2 dopamine receptor agonist.

Features and Benefits

This compound is featured on the α2-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Lagerklasse

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Analysenzertifikate (COA)

Lot/Batch Number
028K4703
023K4700
014K4702

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M R Corboz et al.
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The vascular bed in nasal mucosa of different species, including human, is highly vascularized and an extensive sinusoidal network of large capacitance vessels is present deep within the submucosa. When this network of venous sinusoids is engorged with blood, the
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Hypertension research : official journal of the Japanese Society of Hypertension, 25(2), 197-202 (2002-06-06)
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Minori Enomoto et al.
Movement disorders : official journal of the Movement Disorder Society, 23(6), 811-816 (2007-12-13)
This study was done to identify the clinical characteristics of uremic restless legs syndrome (RLS). Consecutive uremic RLS patients (n = 15) and idiopathic RLS patients (iRLS; n = 20) were evaluated. The groups were compared with respect to their
R C Miller et al.
British journal of pharmacology, 83(4), 903-908 (1984-12-01)
In the presence of endothelium maximal contractions of rat aorta preparations evoked by B-HT 920 were about 10% of those evoked in the absence of endothelium. 6-Allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo-(4,5-d)azepin dihydrochloride (B-HT 920, 0.1 microM to 0.1 mM) induced concentration-dependent contractions of rat
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