A7357

Arachidonoylserotonin

≥98% (HPLC), oil

• Synonym(e): AA-5-HT, N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenamide
• Empirische Formel (Hill-System): C₃₀H₄₂N₂O₂
• CAS-Nummer: 187947-37-1
• Molekulargewicht: 462.67
• UNSPSC Code: 12352200
• PubChem Substance ID: 329770927
• MDL number: MFCD02179189
• Assay: ≥98% (HPLC)
• Form: oil
• Quality level: 100

Eigenschaften

• Quality Level: 100
• InChI: 1S/C30H42N2O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-30(34)31-23-22-26-25-32-29-21-20-27(33)24-28(26)29/h6-7,9-10,12-13,15-16,20-21,24-25,32-33H,2-5,8,11,14,17-19,22-23H2,1H3,(H,31,34)/b7-6-,10-9-,13-12-,16-15-
• SMILES string: CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCc1c[nH]c2ccc(O)cc12
• InChI key: QJDNHGXNNRLIGA-DOFZRALJSA-N
• assay: ≥98% (HPLC)
• form: oil
• color: yellow
• solubility: DMSO: >10 mg/mL
• shipped in: wet ice
• storage temp.: −20°C

Beschreibung

Application

Arachidonoylserotonin is a fatty acid amide hydrolase (FAAH) inhibitor and transient receptor potential vanilloid-type I (TRPV1) antagonist. Both FAAH and TRPV1 are targets for chronic pain treatment. Arachidonoylserotonin has been used in a study to determine the involvement of endovanilloids in the cortical plastic changes associated with peripheral nerve injury.

Biochem/physiol Actions

Arachidonoylserotonin is a Fatty Acid Amide Hydrolase (FAAH) Inhibitor and Transient Receptor Potential Vanilloid-Type I (TRPV1) Antagonist.

Arachidonoylserotonin is a Fatty Acid Amide Hydrolase (FAAH) Inhibitor and Transient Receptor Potential Vanilloid-Type I (TRPV1) Antagonist. FAAH and TRPV1 are targets for chronic pain treatment. Arachidonylserotonin is a dual target agent and is analgesic in rodents.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)