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A4375

Sigma-Aldrich

N-Acetyl-D-alanine

≥98% (TLC), suitable for ligand binding assays

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About This Item

Empirische Formel (Hill-System):
C5H9NO3
CAS-Nummer:
19436-52-3
Molekulargewicht:
131.13
EG-Nummer:
243-066-8
MDL-Nummer:
MFCD00063133
UNSPSC-Code:
12352209
eCl@ss:
32160406
PubChem Substanz-ID:
24890850
NACRES:
NA.26

product name

N-Acetyl-D-alanine,

Assay

≥98% (TLC)

Form

powder

Methode(n)

ligand binding assay: suitable

Farbe

white to off-white

Lagertemp.

−20°C

SMILES String

C[C@@H](NC(C)=O)C(O)=O

InChI

1S/C5H9NO3/c1-3(5(8)9)6-4(2)7/h3H,1-2H3,(H,6,7)(H,8,9)/t3-/m1/s1

InChIKey

KTHDTJVBEPMMGL-GSVOUGTGSA-N

Biochem./physiol. Wirkung

N-Acetyl-D-alanine may be used with other D-aminoacylated amino acids as a substrate for the identification, differentiation and characterization of D-aminoacylase(s)/amidohydrolase(s). N-acetyl-D-alanine may be used to study aglycon pocket specific binding on vancomycin.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Yasushi Nitanai et al.
Journal of molecular biology, 385(5), 1422-1432 (2008-11-04)
The crystal structures of three vancomycin complexes with two vancomycin-sensitive cell-wall precursor analogs (diacetyl-Lys-D-Ala-D-Ala and acetyl-D-Ala-D-Ala) and a vancomycin-resistant cell-wall precursor analog (diacetyl-Lys-D-Ala-D-lactate) were determined at atomic resolutions of 1.80 A, 1.07 A, and 0.93 A, respectively. These structures not
P J Loll et al.
Chemistry & biology, 5(5), 293-298 (1998-05-14)
Vancomycin and related glycopeptide antibiotics exert their antimicrobial effect by binding to carboxy-terminal peptide targets in the bacterial cell wall and preventing the biosynthesis of peptidoglycan. Bacteria can resist the action of these agents by replacing the peptide targets with
Ines Slama et al.
Journal of chromatographic science, 40(2), 83-86 (2002-03-08)
The analysis of the binding data of D,L-dansyl amino acids on a vancomycin stationary phase is investigated in relation to the addition of N-acetyl-D-alanine in the mobile phase. This eluent additive acts as a specific competing agent for the aglycone
David J Merkler et al.
Bioorganic & medicinal chemistry, 16(23), 10061-10074 (2008-10-28)
Peptidyl alpha-hydroxylating monooxygenase (PHM) functions in vivo towards the biosynthesis of alpha-amidated peptide hormones in mammals and insects. PHM is a potential target for the development of inhibitors as drugs for the treatment of human disease and as insecticides for

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