Adenosin-5′-triphosphat (ATP) spielt eine zentrale Rolle bei der Energiespeicherung und im Energiestoffwechsel in vivo. ATP ist an vielen Zellprozessen, der Atmung, Biosynthesereaktionen, Motilität und Zellteilung beteiligt. ATP ist ein Substrat aus zahlreichen, an der zellulären Signalgebung beteiligten Kinasen und Adenylatcyklasen, die den sekundären Botenstoff cAMP produzieren. ATP stellt die Stoffwechselenergie zum Antrieb von Stoffwechselpumpen bereit. ATP dient in vielen verschiedenen enzymatischen Reaktionen als Coenzym.
Biochem./physiol. Wirkung
P2 Purinoceptor Antagonist.
P2 purinergener Antagonist; erhöht die Aktivität von Ca2+-aktivierten K+ Kanälen; Substrat für ATP-abhängigen Enzymsysteme.
Langmuir : the ACS journal of surfaces and colloids, 25(3), 1582-1587 (2009-01-28)
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The AAA+ protein disaggregase, Hsp104, increases fitness under stress by reversing stress-induced protein aggregation. Natural Hsp104 variants might exist with enhanced, selective activity against neurodegenerative disease substrates. However, natural Hsp104 variation remains largely unexplored. Here, we screened a cross-kingdom collection
International journal of molecular sciences, 21(23) (2020-12-10)
Acute or chronic administration of guanosine (GUO) induces anxiolytic-like effects, for which the adenosine (ADO) system involvement has been postulated yet without a direct experimental evidence. Thus, we aimed to investigate whether adenosine receptors (ARs) are involved in the GUO-mediated
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Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..
