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A2027

Sigma-Aldrich

L-Arginine-7-amido-4-methylcoumarin hydrochloride

cathepsin H substrate

Synonym(e):

Arginine 4-methyl-7-coumarylamide

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About This Item

Empirische Formel (Hill-System):
C16H21N5O3
CAS-Nummer:
69304-16-1
Molekulargewicht:
331.37
MDL-Nummer:
MFCD00058184
UNSPSC-Code:
12352204
PubChem Substanz-ID:
24890618
NACRES:
NA.83

Assay

≥97% (TLC)

Form

powder

Löslichkeit

acetic acid: water (1:1): 50 mg/mL, clear, colorless to light yellow

Lagertemp.

−20°C

SMILES String

Cl.CC1=CC(=O)Oc2cc(NC(=O)[C@@H](N)CCCNC(N)=N)ccc12

InChI

1S/C16H21N5O3.ClH/c1-9-7-14(22)24-13-8-10(4-5-11(9)13)21-15(23)12(17)3-2-6-20-16(18)19;/h4-5,7-8,12H,2-3,6,17H2,1H3,(H,21,23)(H4,18,19,20);1H/t12-;/m0./s1

InChIKey

PFLMUQNBZRXRHD-YDALLXLXSA-N

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Anwendung

L-Arginine-7-amido-4-methylcoumarin hydrochloride has been used as a substrate for cathepsin H from rat muscle homogenate and sarcoplasmic extract. It has also been used as a substrate for arginine amino-peptidase from Daphnia homogenates and recombinant aminopeptidase from Toxoplasma gondii.

Biochem./physiol. Wirkung

L-Arginine-7-amido-4-methylcoumarin hydrochloride is a protease substrate. It is a specific substrate for cathepsin H and not for cathepsin L and B.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

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Sigma-Aldrich

M1381

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