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A1263

Sigma-Aldrich

DL-Amphetamin -sulfat (Salz)

Synonym(e):

(±)-α-Methylphenethylamine sulfate salt

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About This Item

Lineare Formel:
C18H26N2 · H2SO4
CAS-Nummer:
60-13-9
Molekulargewicht:
368.49
EG-Nummer:
200-457-8
MDL-Nummer:
MFCD00070254
UNSPSC-Code:
12352116
PubChem Substanz-ID:
329770696
NACRES:
NA.77

Form

powder

Qualitätsniveau

100

Arzneimittelkontrolle

USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada

Anwendung(en)

forensics and toxicology

SMILES String

OS(O)(=O)=O.CC(N)Cc1ccccc1.CC(N)Cc2ccccc2

InChI

1S/2C9H13N.H2O4S/c2*1-8(10)7-9-5-3-2-4-6-9;1-5(2,3)4/h2*2-6,8H,7,10H2,1H3;(H2,1,2,3,4)

InChIKey

PYHRZPFZZDCOPH-UHFFFAOYSA-N

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Anwendung

DL-Amphetamine sulfate salt has been used to induce place preference in rats to study the effect of diazepam and zolpidem. It has also been used as a drug standard in the digital image-based colorimetric presumptive test.

Biochem./physiol. Wirkung

DL -Amphetamine, also known as benzedrine, is a synthetic stimulant. It is usually produced as a sulfate salt (DL-amphetamine sulfate salt). DL-Amphetamine sulfate may be used to treat children with behavior disorders., Induces release of catecholamines and serotonin by displacing the monoamines from their vesicular storage sites; blocks catecholamine reuptake.

Piktogramme

Skull and crossbonesHealth hazard
GHS06,GHS08

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Chronic 3 - Repr. 2 - STOT RE 2 - STOT SE 3

Zielorgane

Brain, Respiratory system

Lagerklassenschlüssel

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Analysenzertifikate (COA)

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Madeleine P Strohl
The Yale journal of biology and medicine, 84(1), 27-33 (2011-04-01)
In 1937, psychiatrist Charles Bradley administered Benzedrine sulfate, an amphetamine, to "problem" children at the Emma Pendleton Bradley Home in Providence, Rhode Island, in an attempt to alleviate headaches; however, Bradley noticed an unexpected effect upon the behavior of the
E Meririnne et al.
Pharmacology, biochemistry, and behavior, 62(1), 159-164 (1999-02-11)
Drugs such as benzodiazepines, which enhance the effects of inhibitory neurotransmitter gamma-amino butyric acid (GABA), are known to modulate the mesocorticolimbic dopaminergic system, which is considered to mediate the rewarding effects of psychostimulants. The effects of diazepam, a benzodiazepine that
Aree Choodum et al.
Drug testing and analysis, 3(5), 277-282 (2011-03-10)
Digital image analysis was applied to the products of simple colorimetric [corrected] tests for amphetamine and methylamphetamine. Adobe Photoshop software was used for colour analysis to obtain analytical data in the form of a Red Green Blue (RGB) value. Calibration
Rita Perfeito et al.
Free radical biology & medicine, 62, 186-201 (2013-06-08)
Parkinson disease (PD) is a chronic and progressive neurological disease associated with a loss of dopaminergic neurons. In most cases the disease is sporadic but genetically inherited cases also exist. One of the major pathological features of PD is the
Meagan L Auger et al.
The European journal of neuroscience, 38(6), 2853-2863 (2013-06-07)
DCC and UNC5 homologs (UNC5H) are guidance cue receptors highly expressed by mesocorticolimbic dopamine neurons. We have shown that dcc heterozygous mice exhibit increased dopamine, but not norepinephrine, innervation and function in medial prefrontal cortex. Concomitantly, dcc heterozygotes show blunted
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