A0355

AC-7954

≥98% (HPLC), solid

• Synonym(e): (±)-3-(4-Chlorophenyl)-3-(2-(dimethylamino)ethyl)isochroman-1-one hydrochloride
• Empirische Formel (Hill-System): C₁₉H₂₀ClNO₂ · HCl
• CAS-Nummer: 477313-09-0
• Molekulargewicht: 366.28
• NACRES: NA.77
• PubChem Substance ID: 24724382
• UNSPSC Code: 12352202
• MDL number: MFCD07784497
• Assay: ≥98% (HPLC)
• Form: solid

Eigenschaften

• InChI key: AJPGLOWFIBOGMH-UHFFFAOYSA-N
• SMILES string: Cl.CN(C)CCC1(Cc2ccccc2C(=O)O1)c3ccc(Cl)cc3
• InChI: 1S/C19H20ClNO2.ClH/c1-21(2)12-11-19(15-7-9-16(20)10-8-15)13-14-5-3-4-6-17(14)18(22)23-19;/h3-10H,11-13H2,1-2H3;1H
• assay: ≥98% (HPLC)
• form: solid
• color: white
• solubility: H₂O: ~28 mg/mL
• Gene Information: human ... UTS2R(2837)

Beschreibung

Biochem/physiol Actions

Nonpeptide GPR14 / urotensin-UII (UII) receptor agonist that has an EC₅₀ of 300 nM at the human UII receptor (h-UTR).[1] AC-7954 has been shown to exist in two conformations, A and B; both conformations have a pharmacophoric distance within 0.5 Å of P5U, a potent peptidic UII agonist.[2]

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)