55155

7-Hydroxycumarin-3-carbonsäure

suitable for fluorescence, ≥98.0% (capillary electrophoresis)

• Synonym(e): Umbelliferon-3-carbonsäure
• Empirische Formel (Hill-System): C₁₀H₆O₅
• CAS-Nummer: 779-27-1
• Molekulargewicht: 206.15
• UNSPSC Code: 12352106
• NACRES: NA.32
• PubChem Substance ID: 57651515
• MDL number: MFCD00017491
• Beilstein/REAXYS Number: 384141

Eigenschaften

• Quality Segment: 100
• assay: ≥98.0% (capillary electrophoresis)
• form: solid
• pKa: 7.04
• mp: 261 °C (lit.)
• solubility: DMF: soluble, DMSO: soluble, alcohols: soluble
• fluorescence: λ_ex 342 nm; λ_em 447 nm (pH 4.0), λ_ex 386 nm; λ_em 448 nm in 0.1 M Tris pH 9.0
• suitability: suitable for fluorescence
• SMILES string: OC(=O)C1=Cc2ccc(O)cc2OC1=O
• InChI: 1S/C10H6O5/c11-6-2-1-5-3-7(9(12)13)10(14)15-8(5)4-6/h1-4,11H,(H,12,13)
• InChI key: LKLWLDOUZJEHDY-UHFFFAOYSA-N

Beschreibung

Application

7-Hydroxycoumarin-3-carboxylic acid (7-OHCCA) is used as a fluorogenic substrate for glycosyltransferase assays. 7-OHCCA may be used as a non-cinnamate-class substrate analog to study 4-hydroxycinnamate decarboxylase (4-HCD)-inducing activity in Klebsiella oxytoca cells. It is suitable as a pH indicator.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Auf einem Träger immobilisiert kann es als pH-Sensor fungieren.

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves